1: With C39H60N4O4; scandium tris(trifluoromethanesulfonate) in ethyl acetate
T=35°C; 0.5 h;
2: With 3-chloro-benzenecarboperoxoic acid in ethyl acetate
T=-40°C; Baeyer-Villiger Ketone Oxidation; 18 h; Overall yield = 99 percent; enantioselective reaction;
参考文献
Zhou, Lin; Liu, Xiaohua; Ji, Jie; Zhang, Yuheng; Hu, Xiaolei; Lin, Lili; Feng, Xiaoming
Journal of the American Chemical Society, 2012 , vol. 134, # 41 p. 17023 - 17026,4
isopropyl 1-thio-β-D-galactopyranoside; β-cyclodextrin; CHMO from Brachymonas
T=20°C; microbial Baeyer-Villiger oxidation reaction; 24 h; Title compound not separated from byproducts.;
参考文献
Rudroff, Florian; Rydz, Joanna; Ogink, Freek H.; Fink, Michael; Mihovilovic, Marko D.
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 8-9 p. 1436 - 1444
1.1: trichlorophosphate / diethyl ether / |Reflux
2.1: acetic acid; zinc / 0 - 70 °C
3.1: C39H60N4O4; scandium tris(trifluoromethanesulfonate) / ethyl acetate / 0.5 h / 35 °C
3.2: 18 h / -40 °C
View Scheme
参考文献
Zhou, Lin; Liu, Xiaohua; Ji, Jie; Zhang, Yuheng; Hu, Xiaolei; Lin, Lili; Feng, Xiaoming
Journal of the American Chemical Society, 2012 , vol. 134, # 41 p. 17023 - 17026,4
