2-溴-9,9'-螺二芴合成路线 （共 10 条）
反应条件
acetic acid; sulfuric acid 1 h; Heating;
参考文献
EP2343277 A2, ;
Page/Page column 44-45 ;
反应条件
diisobutylaluminium hydride; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; toluene T=65°C;
参考文献
EP1533289 A1, ;
Page/Page column 23 ;
反应条件
2-biphenylyl lithium Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 38, # 21 p. 3675 - 3678
反应条件
1: diethyl ether / 3 h / Heating 2: conc. H2SO4 / 3 h View Scheme
参考文献
Journal of the American Chemical Society, , vol. 124, # 39 p. 11576 - 11577
反应条件
magnesium in diethyl ether 65 h; Heating;
参考文献
Helvetica Chimica Acta, , vol. 79, # 5 p. 1338 - 1360
反应条件
bromine; iron(III) chloride in dichloromethane 8 h;
参考文献
Chemistry Letters, , vol. 37, # 8 p. 854 - 855
反应条件
1.1: Mg / diethyl ether / Heating 1.2: diethyl ether / Heating 2.1: 10.4 g / conc. HCl / acetic acid / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 67, # 14 p. 4924 - 4936
反应条件
1: 1-bromo-2-phenylbenzene With magnesium in tetrahydrofuran 3 h; Heating; 2: 2-bromofluoren-9-one in tetrahydrofuran Heating; 3: With hydrogenchloride; acetic acid Heating; Further stages.;
参考文献
Synthetic Communications, , vol. 38, # 12 p. 1888 - 1895
反应条件
1: 2-dibromo-9,9'-spirobifluorene With magnesium in tetrahydrofuran Grignard reaction; 16 h; Reflux; 2: N,N-dimethyl-formamide in tetrahydrofuran T=20°C; 16 h; Cooling with ice;
参考文献
Chi, Chih-Chin; Huang, Yu-Jui; Chen, Chin-Ti
Journal of the Chinese Chemical Society, 2012 , vol. 59, # 3 p. 305 - 316
反应条件
1: in N,N-dimethyl-formamide
8 h; Heating;
2: With hydrogenchloride; iron(III) chloride in water; N,N-dimethyl-formamide
T=70°C; 0.5 h;
参考文献
Wong, Ken-Tsung; Ku, Sung-Yu; Cheng, Yi-Ming; Lin, Xiauo-Yun; Hung, Ying-Yueh; Pu, Shih-Chieh; Chou, Pi-Tai; Lee, Gene-Hsiang; Peng, Shie-Ming
Journal of Organic Chemistry, 2006 , vol. 71, # 2 p. 456 - 465
