alpha-甲基-(7ci,8ci,9ci)-2-苯并噻唑甲醇合成路线 （共 7 条）
反应条件
1: cyclobenzothiazole With n-butyllithium in tetrahydrofuran; n-heptane T=-78°C; 1 h; 2: acetaldehyde in tetrahydrofuran; n-heptane T=-70 - -10°C; 2 h; Further stages.;
参考文献
Alatorre-Santamaria, Sergio; Gotor-Fernandez, Vicente; Gotor, Vicente
European Journal of Organic Chemistry, 2009 , # 15 p. 2533 - 2538
反应条件
tert.-butylhydroperoxide in decane T=120°C; 6 h; sealed tubeunder air;
参考文献
He, Tao; Yu, Lin; Zhang, Lei; Wang, Lei; Wang, Min
Organic Letters, 2011 , vol. 13, # 19 p. 5016 - 5019
参考文献
Florio, Saverio; Capriati, Vito; Colli, Gennara
Tetrahedron, 1997 , vol. 53, # 16 p. 5839 - 5846
反应条件
1: K2Cr2O7 / acetic acid / 1 h / Heating 2: Br2 / CHCl3 View Scheme
参考文献
Sawhney,S.N.; Singh,J.
Indian Journal of Chemistry, 1970 , vol. 8, p. 882 - 884
反应条件
pyridinium chlorochromate in dichloromethane T=20°C; 10 h;
参考文献
Tosa, Monica Ioana; Podea, Paula Veronica; Paizs, Csaba; Irimie, Florin Dan
Tetrahedron Asymmetry, 2008 , vol. 19, # 17 p. 2068 - 2071
反应条件
1: K2Cr2O7 / acetic acid / 1 h / Heating
2: Br2 / CHCl3
3: diethyl ether; benzene / Heating
View Scheme
参考文献
Sawhney,S.N.; Singh,J.
Indian Journal of Chemistry, 1970 , vol. 8, p. 882 - 884
反应条件
1: 61 percent / CH3SO2Cl, Et3N / 1) 0 deg C -> room temperature, 30 min, 2) reflux, 2 h
2: 64 percent / t-BuO(1-) / 2-methyl-propan-2-ol / Heating
View Scheme
参考文献
Florio, Saverio; Capriati, Vito; Colli, Gennara
Tetrahedron, 1997 , vol. 53, # 16 p. 5839 - 5846
