1,4-双(三丁基甲锡烷基)苯合成路线 （共 10 条）
反应条件
magnesium; ethylene dibromide in tetrahydrofuran T=20°C; Barbier Coupling Reaction; 4 h; SonicationInert atmosphere;
参考文献
Gerbino, Dario C.; Fidelibus, Pablo M.; Mandolesi, Sandra D.; Ocampo, Romina A.; Scoccia, Jimena; Podesta, Julio C.
Journal of Organometallic Chemistry, 2013 , vol. 741-742, # 1 p. 24 - 32
反应条件
magnesium; ethylene dibromide in tetrahydrofuran T=20°C; Barbier Coupling Reaction; 4 h; SonicationInert atmosphere;
参考文献
Gerbino, Dario C.; Fidelibus, Pablo M.; Mandolesi, Sandra D.; Ocampo, Romina A.; Scoccia, Jimena; Podesta, Julio C.
Journal of Organometallic Chemistry, 2013 , vol. 741-742, # 1 p. 24 - 32
反应条件
tert.-butyl lithium in tetrahydrofuran; pentane stirring (-78°C,1 h), addn. of n-Bu3SnCl, warming, stirring (roomtemp., overnight); quenching with NH4Cl, extn. (Et2O), vacuum distillation;
参考文献
Koo, Sangho; Liebeskind, Lanny S.
Journal of the American Chemical Society, 1995 , vol. 117, # 12 p. 3389 - 3404
反应条件
palladium diacetate; potassium fluoride; tert-octyl isocyanide in tetrahydrofuran 20°C, 24 h, in the presence of (18)crown-6; no reaction;
参考文献
Yoshida, Hiroto; Tanino, Kenji; Ohshita, Joji; Kunai, Atsutaka
Angewandte Chemie - International Edition, 2004 , vol. 43, # 38 p. 5052 - 5055
反应条件
in diethyl ether addn. of soln. of org. compd. in ether to Sn-compd. and Mg in ether with reflux within 1 h, refluxing (23 h); cooling (5°C), shaking (ice-cold aq. HCl), sepn. of etheral layer, washing (brine), drying (Na2SO4), evapn., distn.; elem. anal.;
参考文献
Morgan, Jacqueline; Pinhey, John T.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , p. 715 - 720
反应条件
in 1,2-dichloro-benzene T=180°C; 2.5 h; Inert atmosphere;
参考文献
Journal of Organometallic Chemistry, , vol. 694, # 22 p. 3674 - 3678
反应条件
bis-triphenylphosphine-palladium(II) chloride Stille Cross Coupling; 0.5 h; Irradiation;
参考文献
Luong, Martin; Domini, Claudia E.; Silbestri, Gustavo F.; Chopa, Alicia B.
Journal of Organometallic Chemistry, 2013 , vol. 723, p. 43 - 48
反应条件
in 1,2-dichloro-benzene T=180°C; 2.5 h; Inert atmosphere;
参考文献
Lo Fiego, Marcos J.; Lockhart, Maria T.; Chopa, Alicia B.
Journal of Organometallic Chemistry, 2009 , vol. 694, # 22 p. 3674 - 3678
反应条件
bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide
T=100°C; 19 h;
参考文献
Havelkova, Martina; Dvorak, Dalimil; Hocek, Michal
Tetrahedron, 2002 , vol. 58, # 37 p. 7431 - 7435
反应条件
1: 23 percent / Pd(PPh3)2Cl2 / dimethylformamide / 19 h / 100 °C
2: 35 percent / Pd(PPh3)2Cl2 / dimethylformamide / 3.5 h / 100 °C
View Scheme
参考文献
Havelkova, Martina; Dvorak, Dalimil; Hocek, Michal
Tetrahedron, 2002 , vol. 58, # 37 p. 7431 - 7435
