4-[(5,6-二氢-5,5-二甲基-8-(4-甲基苯基)-2-萘)乙炔]苯甲酸乙酯合成路线 （共 22 条）
反应条件
tert.-butyl lithium; Zinc chloride; tetrakis (triphenylphosphine) palladium (0) in tetrahydrofuran; pentane
参考文献
US5958954 A1, ;
US 5958954 A
反应条件
tert.-butyl lithium; Zinc chloride; tetrakis (triphenylphosphine) palladium (0) in tetrahydrofuran; pentane
参考文献
US5958954 A1, ;
US 5958954 A
反应条件
tert.-butyl lithium; Zinc chloride; tetrakis (triphenylphosphine) palladium (0) in tetrahydrofuran; pentane
参考文献
US5958954 A1, ;
US 5958954 A
反应条件
tert.-butyl lithium; Zinc chloride; tetrakis (triphenylphosphine) palladium (0) in tetrahydrofuran; pentane
参考文献
US5958954 A1, ;
US 5958954 A
反应条件
n-butyllithium; Zinc chloride; tetrakis (triphenylphosphine) palladium (0) in tetrahydrofuran; hexane
参考文献
US5958954 A1, ;
US 5958954 A
反应条件
Zinc chloride; tetrakis (triphenylphosphine) palladium (0) in tetrahydrofuran
反应条件
1: 80 percent / AlCl3, Br2 / CH2Cl2 / 70 °C 2: (PPh3)2PdCl2, CuI, Et2NH / 60 °C 3: K2CO3 / methanol / Ambient temperature 4: 64 percent / (PPh3)2PdCl2, CuI, Et2NH / Ambient temperature 5: 1.) NaN(SiMe3)2 / 1.) THF, -78 deg C, 2.) THF, from 0 deg C to RT 6: 1.) t-BuLi, 2.) ZnCl2, 3.) Pd(PPh3)4 View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 24 p. 4764 - 4767
反应条件
1: (PPh3)2PdCl2, CuI, Et2NH / 60 °C 2: K2CO3 / methanol / Ambient temperature 3: 64 percent / (PPh3)2PdCl2, CuI, Et2NH / Ambient temperature 4: 1.) NaN(SiMe3)2 / 1.) THF, -78 deg C, 2.) THF, from 0 deg C to RT 5: 1.) t-BuLi, 2.) ZnCl2, 3.) Pd(PPh3)4 View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 24 p. 4764 - 4767
反应条件
1: K2CO3 / methanol / Ambient temperature 2: 64 percent / (PPh3)2PdCl2, CuI, Et2NH / Ambient temperature 3: 1.) NaN(SiMe3)2 / 1.) THF, -78 deg C, 2.) THF, from 0 deg C to RT 4: 1.) t-BuLi, 2.) ZnCl2, 3.) Pd(PPh3)4 View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 24 p. 4764 - 4767
反应条件
1: 64 percent / (PPh3)2PdCl2, CuI, Et2NH / Ambient temperature 2: 1.) NaN(SiMe3)2 / 1.) THF, -78 deg C, 2.) THF, from 0 deg C to RT 3: 1.) t-BuLi, 2.) ZnCl2, 3.) Pd(PPh3)4 View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 24 p. 4764 - 4767
