4-[2-[5,6-二氢-5,5-二甲基-8-[[(三氟甲基)磺酰基]氧基]-2-萘基]乙炔基]苯甲酸乙酯合成路线 (共 24 条)
反应条件
tert.-butyl lithium; Zinc chloride; tetrakis (triphenylphosphine) palladium (0) in tetrahydrofuran; pentane
参考文献
Allergan Sales, Inc.
Patent: US5958954 A1, 1999 ;
US 5958954 A
反应条件
n-butyllithium; Zinc chloride; tetrakis (triphenylphosphine) palladium (0) in tetrahydrofuran; hexane
参考文献
Allergan Sales, Inc.
Patent: US5958954 A1, 1999 ;
US 5958954 A
反应条件
Zinc chloride; tetrakis (triphenylphosphine) palladium (0) in tetrahydrofuran
参考文献
Allergan Sales, Inc.
Patent: US5877207 A1, 1999 ;
反应条件
tetrakis(triphenylphosphine) palladium(0); tert.-butyl lithium; zinc(II) chloride Yield given. Multistep reaction;
参考文献
Johnson; Klein; Gillett; Wang; Song; Pino; Chandraratna
Journal of Medicinal Chemistry, 1995 , vol. 38, # 24 p. 4764 - 4767