1-(1-羟基环戊基)-乙酮合成路线 （共 14 条）
反应条件
in chloroform T=50°C; 3 h;
参考文献
Janout, Vaclav; Regen, Steven L.
Journal of Organic Chemistry, 1982 , vol. 47, # 17 p. 3331 - 3333
反应条件
N-bromosuccinmide; water in 1,4-dioxane 2 h; Ambient temperature;
参考文献
Gravestock, Michael B.; Morton, Douglas R.; Boots, Sharon G.; Johnson, William S.
Journal of the American Chemical Society, 1980 , vol. 102, # 2 p. 800 - 807
反应条件
1: 37 percent / sodium hydride / dimethylsulfoxide; diethyl ether / 1.5 h / Ambient temperature 2: 50 percent / LiAlH4 / tetrahydrofuran / 2 h / Heating 3: 92.3 mg / N-bromosuccinimide, water / dioxane / 2 h / Ambient temperature View Scheme
参考文献
Journal of the American Chemical Society, , vol. 102, # 2 p. 800 - 807
反应条件
1: 50 percent / LiAlH4 / tetrahydrofuran / 2 h / Heating 2: 92.3 mg / N-bromosuccinimide, water / dioxane / 2 h / Ambient temperature View Scheme
参考文献
Journal of the American Chemical Society, , vol. 102, # 2 p. 800 - 807
反应条件
tetraethylammonium p-toluenesulfonate in ethanol T=5°C; electroreduction (Sn-cathode);
参考文献
Journal of Organic Chemistry, , vol. 57, # 28 p. 7175 - 7187
反应条件
1.1: n-BuLi / tetrahydrofuran; hexane / -78 - -10 °C 1.2: tetrahydrofuran; hexane / -78 °C 2.1: Hg(ClO4)2; MeOH / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 50, # 7 p. 1445 - 1448
反应条件
methanol; mercury(II) perchlorate T=20°C;
参考文献
Journal of Medicinal Chemistry, , vol. 50, # 7 p. 1445 - 1448
反应条件
diethyl ether; methylmagnesium bromide anschliessendes Behandeln mit wss.NH4Cl und Erwaermen des Reaktionsprodukts in Aether mit wss.HCl;
参考文献
Bulletin de la Societe Chimique de France, , p. 784,788
Bulletin de la Societe Chimique de France, , p. 522,530
反应条件
hydrogenchloride; lithium diisopropyl amide 1.) THF, -78 deg C, 45 min, 2.) THF, -78 deg C, 5 h, 3.) THF, 24 h, r.t.; Yield given. Multistep reaction;
参考文献
Chemistry Letters, , p. 71 - 72
反应条件
1: diethyl ether; hydrogen chloride 2: methyl magnesium bromide; diethyl ether / anschliessendes Behandeln mit wss.NH4Cl und Erwaermen des Reaktionsprodukts in Aether mit wss.HCl View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 784,788
