1.1: 60 percent / NBS; benzoyl peroxide / CCl4 / 1 h / 70 °C 2.1: LDA / toluene; tetrahydrofuran; hexane / 2 h / -78 °C 2.2: tetrahydrofuran; toluene; hexane / 3 h / -78 - 0 °C 3.1: 82.0 mg / tetrabutylammonium fluoride / tetrahydrofuran / 1.5 h / 20 °C 4.1: 55 percent / SnCl4 / CH2Cl2 / 1 h / 0 °C 5.1: splG; DTT; KCl / (S)-adenosylmethionine / various solvent(s) / 12 h / 4 °C View Scheme

1.1: 60 percent / NBS; benzoyl peroxide / CCl4 / 1 h / 70 °C 2.1: LDA / toluene; tetrahydrofuran; hexane / 2 h / -78 °C 2.2: tetrahydrofuran; toluene; hexane / 3 h / -78 - 0 °C 3.1: 82.0 mg / tetrabutylammonium fluoride / tetrahydrofuran / 1.5 h / 20 °C 4.1: 55 percent / SnCl4 / CH2Cl2 / 1 h / 0 °C 5.1: splG; DTT; KCl / (S)-adenosylmethionine / various solvent(s) / 12 h / 4 °C View Scheme