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结构式
乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
171623-07-7
合成路线
(共 5 条)
171623-05-5
→
反应条件
171623-07-7
反应条件
sulfur trioxide pyridine complex; triethylamine in dichloromethane; dimethyl sulfoxide T=0 - 20°C; Inert atmosphere;
参考文献
Bartoli, Giuseppe; Di Antonio, Giustino; Fiocchi, Roberto; Giuli, Sandra; Marcantoni, Enrico; Marcolini, Mauro
Synthesis, 2009 , # 6 art. no. Z24108SS, p. 951 - 956
95715-85-8
BOC-D-丝氨酸甲酯
→
反应条件
171623-07-7
反应条件
1: 83 percent / TsOH*H2O / benzene / 36 h / Heating 2: 92 percent / NaBH4, LiCl / ethanol; tetrahydrofuran / 4 h / Ambient temperature 3: 75 percent / Dess-Martin periodinane / CH2Cl2 / 1 h View Scheme
参考文献
Williams, Lorenzo; Zhang, Zhongda; Shao, Feng; Carroll, Patrick J.; Joullie, Madeleine M.
Tetrahedron, 1996 , vol. 52, # 36 p. 11673 - 11694
171623-06-6
→
反应条件
171623-07-7
反应条件
1: 92 percent / NaBH4, LiCl / ethanol; tetrahydrofuran / 4 h / Ambient temperature 2: 75 percent / Dess-Martin periodinane / CH2Cl2 / 1 h View Scheme
参考文献
Williams, Lorenzo; Zhang, Zhongda; Shao, Feng; Carroll, Patrick J.; Joullie, Madeleine M.
Tetrahedron, 1996 , vol. 52, # 36 p. 11673 - 11694
1159706-81-6
→
反应条件
171623-07-7
反应条件
1: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C 2: sulfur trioxide pyridine complex; triethylamine / dichloromethane; dimethyl sulfoxide / 0 - 20 °C / Inert atmosphere View Scheme
参考文献
Bartoli, Giuseppe; Di Antonio, Giustino; Fiocchi, Roberto; Giuli, Sandra; Marcantoni, Enrico; Marcolini, Mauro
Synthesis, 2009 , # 6 art. no. Z24108SS, p. 951 - 956
152491-85-5
(R)-(+)-N-(叔丁氧基羰基)-O-(叔丁基二甲基甲硅烷基)丝氨酸醇
→
反应条件
171623-07-7
反应条件
1: toluene-4-sulfonic acid / water; benzene / 24 h / Reflux 2: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 20 °C 3: sulfur trioxide pyridine complex; triethylamine / dichloromethane; dimethyl sulfoxide / 0 - 20 °C / Inert atmosphere View Scheme
参考文献
Bartoli, Giuseppe; Di Antonio, Giustino; Fiocchi, Roberto; Giuli, Sandra; Marcantoni, Enrico; Marcolini, Mauro
Synthesis, 2009 , # 6 art. no. Z24108SS, p. 951 - 956