4-甲氧基-3-甲基联苯合成路线 （共 53 条）
反应条件
potassium permanganate
参考文献
Dauben; Tanabe
Journal of the American Chemical Society, 1953 , vol. 75, p. 4969,4972
反应条件
1: KMnO4 2: aqueous HBr; acetic acid View Scheme
参考文献
Journal of the American Chemical Society, , vol. 75, p. 4969,4972
反应条件
NHC-Pd(II)-Im; potassium tert-butylate in water
T=80°C; Suzuki-Miyaura coupling; 12 h;
参考文献
Tang, Yi-Qiang; Lu, Jian-Mei; Shao, Li-Xiong
Journal of Organometallic Chemistry, 2011 , vol. 696, # 23 p. 3741 - 3744
反应条件
8C33H27N9O3*6Pd(2+)*12NO3(1-); potassium carbonate in ethanol; water
T=60°C; Suzuki-Miyaura Coupling; 10 h; Green chemistry;
参考文献
Zhao, Chao-Wei; Ma, Jian-Ping; Liu, Qi-Kui; Yu, Yang; Wang, Peng; Li, Yan-An; Wang, Kui; Dong, Yu-Bin
Green Chemistry, 2013 , vol. 15, # 11 p. 3150 - 3154
反应条件
potassium carbonate; [PS-PEG-adppp-Pd(η3-C3H5)]Cl in water
T=50°C; Suzuki-Miyaura coupling; 12 h;
参考文献
Uozumi, Yasuhiro; Nakai, Yasushi
Organic Letters, 2002 , vol. 4, # 17 p. 2997 - 3000
反应条件
K3PO4*3H2O; PdCl2(C3H3N2(CH3))(C3H2N2(C6H3(C3H7)2)2) in tetrahydrofuran; water
T=20°C; Suzuki-Miyaura coupling reaction; 24 h; Inert atmosphere;
参考文献
Tang, Yi-Qiang; Lu, Jian-Mei; Shao, Li-Xiong
Journal of Organometallic Chemistry, 2011 , vol. 696, # 23 p. 3741 - 3744
反应条件
1: 1-chloro-3-methylbenzene With HASPO; Ni(acac)2 in tetrahydrofuran
T=20°C; 0.0833333 h;
2: 4-methoxyphenyl magnesium bromide in tetrahydrofuran
T=20°C; Kumada cross-copling; 4 h;
参考文献
Ackermann, Lutz; Born, Robert; Spatz, Julia H.; Meyer, Daniel
Angewandte Chemie - International Edition, 2005 , vol. 44, # 44 p. 7216 - 7219
反应条件
tris-(dibenzylideneacetone)dipalladium(0); tert.-butylnitrite; trifuran-2-yl-phosphane; acetic acid in N,N-dimethyl-formamide
T=90°C; 8 h; Inert atmosphere;
参考文献
Mo, Fanyang; Qiu, Di; Jiang, Yubo; Zhang, Yan; Wang, Jianbo
Tetrahedron Letters, 2011 , vol. 52, # 4 p. 518 - 522
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; (9-phenanthrenyl)Ni(II)(PPh3)2Cl; potassium carbonate in toluene
T=110°C; Suzuki Coupling; 30 h; Inert atmosphere;
参考文献
Hu, Feng; Lei, Xiangyang
Tetrahedron, 2014 , vol. 70, # 25 p. 3854 - 3858
反应条件
potassium phosphate; Ni(PCy3)2Cl2 in toluene
T=110°C; Suzuki-Miyaura coupling reaction; 24 h; Inert atmosphere;
参考文献
Quasdorf, Kyle W.; Antoft-Finch, Aurora; Liu, Peng; Silberstein, Amanda L.; Komaromi, Anna; Blackburn, Tom; Ramgren, Stephen D.; Houk; Snieckus, Victor; Garg, Neil K.
Journal of the American Chemical Society, 2011 , vol. 133, # 16 p. 6352 - 6363
