4-甲氧基-3-甲基联苯合成路线 （共 53 条）
反应条件
tetrabutylammomium bromide; palladium diacetate in tetrahydrofuran
T=20°C; Negishi coupling; 4 h; Inert atmosphere;
参考文献
Liu, Jing; Deng, Yi; Wang, Haibo; Zhang, Hua; Yu, Ganxiang; Wu, Bingbin; Zhang, Heng; Li, Qiang; Marder, Todd B.; Yang, Zhen; Lei, Aiwen
Organic Letters, 2008 , vol. 10, # 13 p. 2661 - 2664
反应条件
bathophenanthroline; potassium tert-butylate; ferrous acetate
T=20 - 80°C; Inert atmosphere;
参考文献
Vallee, Frederic; Mousseau, James J.; Charette, Andre B.
Journal of the American Chemical Society, 2010 , vol. 132, # 5 p. 1514 - 1516
反应条件
AlCl3, aluminium chloride in 1,4-dioxane
T=20°C; 3.5 h;
参考文献
Narender, Tadigoppula; Sarkar, Satinath; Rajendar, Kandikonda; Tiwari, Sriniwas
Organic Letters, 2011 , vol. 13, # 23 p. 6140 - 6143
反应条件
potassium fluoride; tetrakis-(ethylene)-μ,μ'-dichlorodirhodium(I) in 1,3,5-trimethyl-benzene
T=160°C; Suzuki coupling; 8 h;
参考文献
Goossen; Paetzold
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1665 - 1668
反应条件
caesium carbonate; triphenylphosphine; palladium dichloride in N,N-dimethyl acetamide
T=90°C; 2 h;
参考文献
Rao, Maddali L.N.; Jadhav, Deepak N.; Banerjee, Debasis
Tetrahedron, 2008 , vol. 64, # 24 p. 5762 - 5772
反应条件
Ni(PCy3)2Cl2; tri-cyclo-hexyl-phosphine in diethyl ether
T=20°C; Kumada coupling; 2 h; Inert atmosphere;
参考文献
Guan, Bing-Tao; Lu, Xing-Yu; Zheng, Yang; Yu, Da-Gang; Wu, Tong; Li, Kun-N; Li, Bi-Jie; Shi, Zhang-Jie
Organic Letters, 2010 , vol. 12, # 2 p. 396 - 399
反应条件
caesium carbonate in water; N,N-dimethyl-formamide
T=90°C; Suzuki coupling;
参考文献
Lan, Ping; Berta, Daniela; Porco Jr., John A.; South, Michael S.; Parlow, John J.
Journal of Organic Chemistry, 2003 , vol. 68, # 25 p. 9678 - 9686
反应条件
PPh3 gold(I) chloro complex; silver trifluoromethanesulfonate in dichloromethane
T=23°C; 4.5 h; Inert atmosphereAnhydrous conditions;
参考文献
Bhunia, Sabyasachi; Abu Sohel, Shariar Md.; Yang, Chao-Chin; Lush, Shie-Fu; Shen, Fwu-Ming; Liu, Rai-Shung
Journal of Organometallic Chemistry, 2009 , vol. 694, # 4 p. 566 - 570
反应条件
potassium fluoride in dimethyl sulfoxide
T=105°C; 0.75 h;
参考文献
Zhou, Wen-Jun; Wang, Ke-Hu; Wang, Jin-Xian; Huang, Dan-Feng
European Journal of Organic Chemistry, 2010 , # 3 p. 416 - 419
反应条件
sodium carbonate; palladium dichloride in methanol
T=20°C; Suzuki-Miyaura cross-coupling reaction; 0.333333 h;
参考文献
Zhou, Wen-Jun; Wang, Ke-Hu; Wang, Jin-Xian; Gao, Zhi-Rong
Tetrahedron, 2010 , vol. 66, # 38 p. 7633 - 7641
