3-羟基-2-甲基-4(1H)-吡啶酮合成路线 （共 6 条）
反应条件
ammonium hydroxide T=130°C; 0.5 h; Irradiation;
参考文献
Raner, Kevin D.; Strauss, Christopher R.; Trainor, Robert W.; Thorn, John S.
Journal of Organic Chemistry, 1995 , vol. 60, # 8 p. 2456 - 2460
反应条件
hydrogen bromide T=140 - 150°C; 4 h;
参考文献
Hwang; Proctor; Driscoll
Journal of Pharmaceutical Sciences, 1980 , vol. 69, # 9 p. 1074 - 1076
反应条件
hydrogen bromide in acetic acid
参考文献
Nelson, William O.; Karpishin,Timothy B.; Rettig, Steven J.; Orvig, Cris
Canadian Journal of Chemistry, 1988 , vol. 66, p. 123 - 131
反应条件
1: 60 percent / NH3 / ethanol 2: 82 percent / HBr / acetic acid View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 66, p. 123 - 131
反应条件
1: 80.5 percent / NH4OH / 1.) refluxm 12 h, 2.) room temperature, 4 h 2: 77 percent / 48percent HBr / 4 h / 140 - 150 °C View Scheme
参考文献
Journal of Pharmaceutical Sciences, , vol. 69, # 9 p. 1074 - 1076
反应条件
sodium hydroxide in methanol; water 6 h; Heating;
参考文献
Santos, M. Amelia; Gama, Sofia; Gano, Lurdes; Cantinho, Guilhermina; Farkas, Etelka
Dalton Transactions, 2004 , # 21 p. 3772 - 3781
