6-氯-5-硝基吡啶-3-甲酸乙酯合成路线 (共 2 条)
反应条件
1: 6-chloro-5-nitronicotinic acid With thionyl chloride; N,N-dimethyl-formamide 2 h; Reflux; 2: ethanol With N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 17 h;
参考文献
WO2013/152039 A1, ;
Page/Page column 167 ;
反应条件
1: 2-hydroxy 5-pyridine carboxylic acid With nitric acid 2: With trichlorophosphate 3: ethanol
参考文献
US2003/236251 A1, ;
Page 22 ;