(R)-4-苯基-1,3-噁唑啉-2-硫酮合成路线 (共 6 条)
反应条件
sodium hydrogencarbonate in water T=100°C; 0.25 h;
参考文献
Chavda, Sameer; Coulbeck, Elliot; Dingjan, Marco; Eames, Jason; Flinn, Anthony; Northen, Julian
Tetrahedron Asymmetry, 2008 , vol. 19, # 13 p. 1536 - 1548
反应条件
1: (rac)-4-phenyl-1,3-oxazolidine-2-thione With Birman's catalyst; N-ethyl-N,N-diisopropylamine in chloroform T=23°C; Resolution of racemate; 2: isobutyric anhydride With sodium sulfate in chloroform T=23°C; 1 h; Resolution of racemate; enantioselective reaction;
参考文献
Journal of the American Chemical Society, , vol. 134, # 42 p. 17605 - 17612
反应条件
1: (rac)-4-phenyl-1,3-oxazolidine-2-thione With Birman's catalyst; N-ethyl-N,N-diisopropylamine in chloroform T=23°C; Resolution of racemate; 2: isobutyric anhydride With sodium sulfate in chloroform T=23°C; 1 h; Resolution of racemate; enantioselective reaction;
参考文献
Journal of the American Chemical Society, , vol. 134, # 42 p. 17605 - 17612
反应条件
1H-imidazole; 4-(N,N-dimethlyamino)pyridine
参考文献
Synthesis, , # 5 p. 719 - 724
反应条件
methyloxirane in chloroform T=150°C; 1 h; Inert atmosphereMicrowave irradiation;
参考文献
Minor-Villar, Leticia; Tello-Aburto, Rodolfo; Olivo, Horacio F.; Fuentes, Aydee; Romero-Ortega, Moises
Synlett, 2012 , vol. 23, # 19 p. 2835 - 2839
反应条件
carbon disulfide; potassium hydroxide in water T=100°C; 16 h;
参考文献
Delaunay, Dominique; Toupet, Loic; Corre, Maurice Le
Journal of Organic Chemistry, 1995 , vol. 60, # 20 p. 6604 - 6607