(S)-4-苄基-1,3-噻唑烷-2-硫酮合成路线 （共 14 条）
反应条件
carbon disulfide; potassium hydroxide in water T=100°C; 16 h; Inert atmosphereReflux;
参考文献
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA; BURKART, Michael, D.; LACLAIR, James, J.; JONES, Brian, D.; MANDEL, Alexander; VILLA, Reymundo; CASTRO, Januario, E.; KASHYAP, Manoj, Kumar; KUMAR, Deepak
Patent: WO2013/148324 A1, 2013 ;
Location in patent: Paragraph 0158-0159 ;
反应条件
potassium hydroxide in ethanol; water 72 h; Heating;
参考文献
Baiget, Jessica; Cosp, Annabel; Galvez, Erik; Gomez-Pinal, Loreto; Romea, Pedro; Urpi, Felix
Tetrahedron, 2008 , vol. 64, # 24 p. 5637 - 5644
反应条件
methanol; C17H23BN2O T=25°C; P=760.051 Torr; 6 h; Inert atmosphere; chemoselective reaction;
参考文献
Oishi, Shunsuke; Saito, Susumu
Angewandte Chemie - International Edition, 2012 , vol. 51, # 22 p. 5395 - 5399
反应条件
in dichloromethane T=-78°C; 1.33333 h; Inert atmosphere;
参考文献
Tetrahedron Letters, , vol. 54, # 3 p. 252 - 255
反应条件
1: 2 M aq. NaOH / 24 h / Ambient temperature 2: P2S5 / toluene / 48 h / Heating View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 14 p. 2139 - 2145
反应条件
in tetrahydrofuran T=80°C; 0.333333 h;
参考文献
Chen, Ning; Jia, Weiyi; Xu, Jiaxi
European Journal of Organic Chemistry, 2009 , # 33 p. 5841 - 5846
反应条件
Birman's catalyst; methanol; benzoic acid in chloroform-d1 T=20°C; 168 h; Resolution of racemate; enantioselective reaction;
参考文献
Organic Letters, , vol. 15, # 11 p. 2790 - 2793
反应条件
1H-imidazole; 4-(N,N-dimethlyamino)pyridine T=25°C; 14 h; Inert atmosphere;
参考文献
Angewandte Chemie - International Edition, , vol. 50, # 13 p. 3013 - 3016
反应条件
1: (S)-1-(4-benzyl-2-thioxothiazolidin-3-yl)-propan-1-one With titanium tetrachloride; N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=0°C; 0.416667 h; Inert atmosphere; 2: propionyl chloride in tetrahydrofuran T=0°C; 48 h; Inert atmosphere; regioselective reaction;
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 52, # 6 p. 769 - 775
反应条件
1: (S)-1-(4-benzyl-2-thioxothiazolidin-3-yl)-propan-1-one With titanium tetrachloride; N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=0°C; 0.416667 h; Inert atmosphere; 2: phenylacetyl chloride in tetrahydrofuran T=0°C; 48 h; Inert atmosphere; regioselective reaction;
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 52, # 6 p. 769 - 775
