2-甲基-4-苯基-3-丁炔-2-醇合成路线 （共 97 条）
反应条件
{(Pd{Fe(.eta.5-C5H5)(.eta.5-C5H3C(CH3)=NC6H4CH3-4)}(.mu.-Cl))2}; potassium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in acetonitrile
T=110°C; 16 h; Inert atmosphere;
参考文献
Hu, Hao; Yang, Fan; Wu, Yangjie
Journal of Organic Chemistry, 2013 , vol. 78, # 20 p. 10506 - 10511
反应条件
1: 85 percent / CaCl2, CuCl, Cu, 12N HCl / diethyl ether; petroleum ether / 1 h / 5 °C
2: 1.) Mg / 1.) Et2O; 2.) 12 h, RT; 2 h, reflux
View Scheme
参考文献
Coulomb-Delbecq,F. et al.
Bulletin de la Societe Chimique de France, 1976 , p. 533 - 540
反应条件
{(Pd{Fe(.eta.5-C5H5)(.eta.5-C5H3C(CH3)=NC6H4CH3-4)}(.mu.-Cl))2}; potassium carbonate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in acetonitrile
T=110°C; 16 h; Inert atmosphere;
参考文献
Hu, Hao; Yang, Fan; Wu, Yangjie
Journal of Organic Chemistry, 2013 , vol. 78, # 20 p. 10506 - 10511
反应条件
sodium hydroxide; copper(l) iodide in butan-1-ol
24 h; Heating;
参考文献
Kang, Suk-Ku; Yoon, Seok-Keun; Kim, Young-Mook
Organic Letters, 2001 , vol. 3, # 17 p. 2697 - 2699
反应条件
triazole-Au in methanol; water
T=60°C; Meyer-Schuster rearrangement; 3 h;
参考文献
Wang, Dawei; Zhang, Yanwei; Harris, Alexandria; Gautam, Lekh Nath S.; Chen, Yunfeng; Shi, Xiaodong
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 14-15 p. 2584 - 2588
反应条件
[Ir(COD)(SnCl3)Cl(μ-Cl)]2; 1,3-diphenyl-1,3-propanedione in 1,2-dichloro-ethane
T=80°C; 0.583333 h; Inert atmosphere;
参考文献
Chatterjee, Paresh Nath; Roy, Sujit
Tetrahedron, 2011 , vol. 67, # 25 p. 4569 - 4577
反应条件
[Ir(COD)(SnCl3)Cl(μ-Cl)]2 in 1,2-dichloro-ethane
T=45°C; Inert atmosphere; regioselective reaction;
参考文献
Chatterjee, Paresh Nath; Roy, Sujit
Journal of Organic Chemistry, 2010 , vol. 75, # 13 p. 4413 - 4423
反应条件
succinic acid; polyvanadioorganosiloxane (4percent V); Ph2Si(OH)2 in various solvent(s)
T=146 - 150°C;
参考文献
Erman, M. B.; Pribytkova, I. M.; Gulyi, S. E.; Bogomolova, O. A.; Cherkaev, G. V.; et al.
Journal of Organic Chemistry USSR (English Translation), 1989 , vol. 25, # 12.2 p. 2294 - 2301
Zhurnal Organicheskoi Khimii, 1989 , vol. 25, # 12 p. 2557 - 2565
反应条件
sodium hydroxide; copper(l) iodide; tetra-(n-butyl)ammonium iodide; bis-triphenylphosphine-palladium(II) chloride in toluene
T=80°C; Sonogashira coupling; 24 h;
参考文献
Chow; Wan; Low; Yeung
Journal of Organic Chemistry, 2001 , vol. 66, # 5 p. 1910 - 1913
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium tert-butylate; silica gel in dimethyl sulfoxide
T=20 - 110°C; 0.05 h; Inert atmosphereMicrowave irradiation;
参考文献
Wu, Liansheng; Shi, Xiaokang; Xu, Xiaoyun; Liang, Fen; Huang, Guosheng
Journal of Chemical Sciences, 2011 , vol. 123, # 5 p. 697 - 702
