3,5-二甲氧基苯甲酰氯合成路线 （共 90 条）
反应条件
aluminium trichloride in hexane; ethyl acetate
反应条件
3: 28.8 g / fluoroboric acid, sodium nitrite / H2O
4: 7.6 g / warming, distillation
5: 1.) lithium / 1.) ether, 2 h
View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
反应条件
1: diethyl ether
2: Ag2O
3: LiAlH4
4: CCl4; PBr3
View Scheme
参考文献
Carnmalm
Acta Chemica Scandinavica (1947-1973), 1955 , vol. 9, p. 246,249
反应条件
1: 68 percent / tetrahydrofuran / -20 - 20 °C
2: 75 percent / 2N KOH / 2 h / Heating
3: 53 percent / Et3SiH / trifluoroacetic acid / 24 h / 45 °C
View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
反应条件
1: 3 percent / sodium carbonate / dimethylsulfoxide / 24 h / 160 °C
View Scheme
参考文献
Lister; Moratti
Tetrahedron, 2006 , vol. 62, # 43 p. 10208 - 10214
参考文献
Farina; Pinza; Gamba; Pifferi
European Journal of Medicinal Chemistry, 1979 , vol. 14, # 1 p. 27 - 31
反应条件
1: H2, quinoline, sulfur / Pd-BaSO4 / xylene
2: I2, HgO / benzene
View Scheme
参考文献
Dallacker,F.; Leidig,H.
Chemische Berichte, 1979 , vol. 112, # 7 p. 2672 - 2679
反应条件
1: diethyl ether
2: water; HCl
View Scheme
参考文献
Carnmalm
Acta Chemica Scandinavica (1947-1973), 1955 , vol. 9, p. 246,249
Show Details
Abe et al.
Yakugaku Zasshi, 1956 , vol. 76, p. 1094
Chem.Abstr., 1957 , p. 2636
反应条件
(i) Et2O, (ii) aq. HCl; Multistep reaction;
参考文献
Miyahara,Y.
Journal of Heterocyclic Chemistry, 1979 , vol. 16, p. 1147 - 1151
反应条件
1: triethylamine / dichloromethane; tetrahydrofuran / -10 - 20 °C
2: tetrahydrofuran / 0 - 20 °C
3: copper(ll) bromide / chloroform; acetonitrile / 6 h / Reflux
View Scheme
参考文献
E. I. DU PONT DE NEMOURS AND COMPANY; SHARPE, Paula, Louise
Patent: WO2011/17261 A1, 2011 ;
