3,5-二甲氧基苯甲酰胺合成路线 （共 34 条）
反应条件
diethyl ether anschliessendes Behandeln mit Eis und wss.H2SO4 bzw. wss.HCl;
参考文献
Adams; Harfenist; Loewe
Journal of the American Chemical Society, 1949 , vol. 71, p. 1624,1626
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Cram
Journal of the American Chemical Society, 1948 , vol. 70, p. 4244,4247
Journal of the American Chemical Society, 1949 , vol. 71, p. 3887
反应条件
tetrahydrofuran; lithium aluminium tetrahydride
参考文献
Kuehne; Lambert
Journal of the American Chemical Society, 1959 , vol. 81, p. 4278,4283
Organic Syntheses, 1973 , vol. Coll. Vol. V, p. 400
反应条件
2: 28.8 g / fluoroboric acid, sodium nitrite / H2O 3: 7.6 g / warming, distillation 4: 52 percent / lithium chips / 0.75 h 5: boron tribromide, pyridine hydrochloride / CH2Cl2 / 24 h / -78 °C View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
反应条件
2: 28.8 g / fluoroboric acid, sodium nitrite / H2O 3: 7.6 g / warming, distillation 4: 60 percent / lithium chips / 0.5 h 5: boron tribromide, pyridine hydrochloride / CH2Cl2 / 24 h / -78 °C View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
反应条件
2: 28.8 g / fluoroboric acid, sodium nitrite / H2O 3: 7.6 g / warming, distillation View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
反应条件
sodium amalgam; ethanol
参考文献
Mauthner
Journal fuer Praktische Chemie (Leipzig), 1920 , vol. <2> 100, p. 177
参考文献
Mauthner
Journal fuer Praktische Chemie (Leipzig), 1920 , vol. <2> 100, p. 177
反应条件
1: 93 percent / diethyl ether 2: 93 percent / diethyl ether 3: 93 percent / POCl3 / pyridine 4: 92 percent / H2 / 10 percent Pd-C / acetic acid / 4 h 5: 96 percent / BBr3 / CH2Cl2 / cooling View Scheme
参考文献
Buchwald; Browne; Wu; Ji; Bodor
Pharmazie, 2000 , vol. 55, # 3 p. 196 - 201
反应条件
sodium hypobromide T=-15°C;
参考文献
Monatshefte fuer Chemie, , vol. 57, p. 52,58
反应条件
2: 28.8 g / fluoroboric acid, sodium nitrite / H2O 3: 7.6 g / warming, distillation 4: 1.) lithium / 1.) ether, 2 h 5: decarboxylation 6: boron tribromide, pyridine hydrochloride / CH2Cl2 / 24 h / -78 °C View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
