1: methanol; hydrogenchloride 2: ammonium formate / methanol / 1 h / 90 °C / |Microwave irradiation View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: 65 percent / imidazole / dimethylformamide<br />2: 90 percent / Et₃N / CH₂Cl₂ / 0 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1: 70 percent / p-TsOH / dimethylsulfoxide / 16 h / Ambient temperature<br />2: 61 percent / NaOH, TBAHSO₄ / 22 h / 40 &deg;C<br />3: 75 percent / AcOH 80percent / H₂O<br />4: 65 percent / imidazole / dimethylformamide<br />5: 90 percent / Et₃N / CH₂Cl₂ / 0 &deg;C<br /> <br /> &nbsp;