二乙基 2-(2-氰基乙基)丙二酸合成路线 （共 27 条）
反应条件
pyridine; dicobalt octacarbonyl in toluene T=55°C; P=750.06 Torr; 2 h;
参考文献
Sisak, Attila; Ungvary, Ferenc; Marko, Laszlo
Journal of Organic Chemistry, 1990 , vol. 55, # 8 p. 2508 - 2513
反应条件
1: diethyl malonate With sodium ethanolate in ethanol 2: acrylonitrile in ethanol Further stages.;
参考文献
Michael, Joseph P.; De Koning, Charles B.; Van der Westhuyzen, Christiaan W.; Fernandes, Manuel A.
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 17 p. 2055 - 2062
反应条件
ZnCl2*Et2O; allyltributylstannane T=0°C;
参考文献
Journal of the American Chemical Society, , vol. 116, # 1 p. 421 - 422
反应条件
triethylamine in dichloromethane T=0 - 20°C; 2 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 39 p. 7863 - 7868
反应条件
potassium carbonate in acetone 4 h; Heating;
参考文献
Chande, Madhukar S.; Khanwelkar, Rahul R.
Tetrahedron Letters, 2005 , vol. 46, # 45 p. 7787 - 7792
反应条件
ethanol; sodium ethanolate
参考文献
Zhurnal Obshchei Khimii, , vol. 22, p. 1977,1985; engl. Ausg. S. 2027, 2032
Journal of the American Chemical Society, , vol. 72, p. 3699
反应条件
ethanol; sodium ethanolate
参考文献
Zhurnal Obshchei Khimii, , vol. 22, p. 1977,1985; engl. Ausg. S. 2027, 2032
Journal of the American Chemical Society, , vol. 72, p. 3699
反应条件
sodium ethanolate in ethanol 8 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 44, # 24 p. 4170 - 4175
反应条件
1: potassium carbonate / dichloromethane / 20 °C 2: hydroxylamine hydrochloride; triethylamine / ethanol / 1 h / |Reflux 3: triethylamine / dichloromethane / 2 h / 0 - 20 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 39 p. 7863 - 7868
反应条件
1: hydroxylamine hydrochloride; triethylamine / ethanol / 1 h / |Reflux 2: triethylamine / dichloromethane / 2 h / 0 - 20 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 39 p. 7863 - 7868
