6-(4-乙酰氨基-1,8-萘醛酰氨基)己酸合成路线 （共 7 条）
反应条件
1-methyl-pyrrolidin-2-one T=150°C; Substitution;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 17 p. 2479 - 2482
反应条件
pyridine T=80°C; 0.75 h;
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 34, # 10 p. 876 - 878
反应条件
1: 78 percent / Na2Cr2O7, AcOH / 5 h / 22 - 25 °C 2: 88 percent / pyridine / 1.5 h / 60 °C 3: 80 percent / Sn, conc. HCl / ethanol / 2 h / 100 °C 4: 64 percent / pyridine / 0.75 h / 80 °C View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 34, # 10 p. 876 - 878
反应条件
1: 88 percent / pyridine / 1.5 h / 60 °C 2: 80 percent / Sn, conc. HCl / ethanol / 2 h / 100 °C 3: 64 percent / pyridine / 0.75 h / 80 °C View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 34, # 10 p. 876 - 878
反应条件
1: 80 percent / Sn, conc. HCl / ethanol / 2 h / 100 °C 2: 64 percent / pyridine / 0.75 h / 80 °C View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 34, # 10 p. 876 - 878
反应条件
1: 57 percent / HNO3, CH3COOH 2: 78 percent / Na2Cr2O7, AcOH / 5 h / 22 - 25 °C 3: 88 percent / pyridine / 1.5 h / 60 °C 4: 80 percent / Sn, conc. HCl / ethanol / 2 h / 100 °C 5: 64 percent / pyridine / 0.75 h / 80 °C View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 34, # 10 p. 876 - 878
反应条件
1: 56 percent / NMP / 150 °C 2: 62 percent / NMP / 150 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 17 p. 2479 - 2482
