2,6-二氯-4-甲氧基吡啶合成路线 （共 5 条）
反应条件
triethylamine; trichlorophosphate in dichloromethane T=0 - 20°C; 3 h;
参考文献
CHEMIZON (BEIJING), LTD.; XIAO, Dengming; ZHU, Li; WANG, Shixin; LIANG, Zhi; HU, Wei
Patent: WO2010/145197 A1, 2010 ;
Location in patent: Page/Page column 80-81 ;
WO 2010/145197 A1
反应条件
in methanol T=0 - 20°C; 12 h;
参考文献
ALIOS BIOPHARMA, INC.; WANG, Guangyi; BEIGELMAN, Leonid; TRUONG, Anh; NAPOLITANO, Carmela; ANDREOTTI, Daniele; HE, Haiying
Patent: WO2014/31784 A1, 2014 ;
Location in patent: Paragraph 0672 ;
反应条件
in tetrahydrofuran; methanol; mineral oil
参考文献
WO2007/21710 A1, ;
Page/Page column 40 ;
WO 2007/021710 A1
反应条件
potassium carbonate T=65°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 5 p. 1940 - 1943
