1: 2.45 g / pyridinium bromide / 0.02 h / Heating 2: potassium carbonate / acetone / 30 - 35 °C 3: potassium carbonate / acetone / 1) 10-15 min, 40-50 deg C 2) 1 h, 60-70 deg C 4: 62.5 percent / 4 percent aq. sodium carbonate / ethanol / 1 h / Heating 5: 90.8 percent / 10 percent methanolic hydrochloric acid / methanol / 0.25 h / Heating View Scheme

1: 62.5 percent / 4 percent aq. sodium carbonate / ethanol / 1 h / Heating 2: 90.8 percent / 10 percent methanolic hydrochloric acid / methanol / 0.25 h / Heating View Scheme

1: boron trifluoride diethyl etherate / 4 h / 80 °C 2: methanesulfonyl chloride / 50 - 70 °C 3: palladium 10 on activated carbon; ammonium formate / methanol / 70 °C View Scheme

1: boron trifluoride diethyl etherate / 4 h / 80 °C 2: methanesulfonyl chloride / 50 - 70 °C 3: palladium 10 on activated carbon; ammonium formate / methanol / 70 °C View Scheme

Asaccharobacter celatus AHU1763 T=37°C; Anaerobic conditionsCulture mediumEnzymatic reaction;

Asaccharobacter celatus AHU1763 T=37°C; Anaerobic conditionsCulture mediumEnzymatic reaction;

Asaccharobacter celatus AHU1763 T=37°C; Anaerobic conditionsCulture mediumEnzymatic reaction;

1.1: 1H-imidazole / N,N-dimethyl-formamide 2.1: magnesium / tetrahydrofuran; ethylene dibromide / 0.75 h / 35 °C 3.1: hydrogen / palladium/alumina / tetrahydrofuran 4.1: water; potassium fluoride / tetrahydrofuran / Reflux 5.1: boron tribromide / chloroform / Reflux 5.2: pH >= 12 5.3: pH 5.5 - 6.5 View Scheme