2-(2-异丁酰胺-6-氧代-1H-嘌呤-9(6h)-基)乙酸合成路线 （共 3 条）
反应条件
triethylsilane; trifluoroacetic acid in dichloromethane T=0 - 20°C;
参考文献
Liu, Zheng-Chun; Shin, Dong-Sik; Lee, Kyu-Teak; Jun, Bong-Hyun; Kim, Yong-Kweon; Lee, Yoon-Sik
Tetrahedron, 2005 , vol. 61, # 33 p. 7967 - 7973
反应条件
1: 64 percent / NaH / dimethylformamide / 2 h / 0 °C 2: 100 percent / triethylsilane; trifluoroacetic acid / CH2Cl2 / 0 - 20 °C View Scheme
参考文献
Hudson, Robert H. E.; Goncharenko, Mykhaylo; Wallman, Andrew P.; Wojciechowski, Filip
Synlett, 2005 , # 9 art. no. S07604ST, p. 1442 - 1446
反应条件
1: 90 percent / dimethylformamide / 7 h / 150 °C 2: 62 percent / NaH / dimethylformamide / 17 h / 0 - 20 °C 3: 84 percent / CF3COOH; (C2H5)3SiH / CH2Cl2 / 18 h View Scheme
参考文献
Will, David W.; Breipohl, Gerhard; Langner, Dietrich; Knolle, Jochen; Uhlmann, Eugen
Tetrahedron, 1995 , vol. 51, # 44 p. 12069 - 12082
