5-氯磺酰基-2-羟基苯甲酸合成路线 （共 17 条）
反应条件
water; sodium acetate
T=70 - 80°C;
参考文献
Bayer and Co.
Patent: DE276331 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 12, p. 175
反应条件
1: 85 percent / sodium sulfite, 20percent aq. NaOH / H2O
2: 1.) Na2CO3, 2.) 10percent aq. NaOH / 1.) CH3OH, reflux, 48h, 2.) aq. EtOH, reflux, 24 h
View Scheme
参考文献
Clark; Coburn; Evans; Genco
Journal of Medicinal Chemistry, 1986 , vol. 29, # 1 p. 25 - 29
反应条件
sodium hydrogencarbonate in 1,4-dioxane
T=50°C;
参考文献
Fel'dman,I.Kh.; Vinokurova,N.M.
J. Gen. Chem. USSR (Engl. Transl.), 1963 , vol. 33, p. 394 - 396,388 - 390
反应条件
triethylamine in dichloromethane
T=20°C; 16 h;
参考文献
Olsen, Helle Birk; kaarsholm, Niels C.; Madsen, Peter; Ostergaard, Soren; Ludvigsen, Svend; Jakobsen, Palle; Petersen, Anders Klarskov; Steensgaard, Dorte Bjerre
Patent: US2003/229120 A1, 2003 ;
Location in patent: Page 84 ;
参考文献
Cremlyn, Richard; Swinbourne, Frederick; Atherall, John; Courtney, Lynn; Cronje, Theo; at al.
Phosphorus and Sulfur and the Related Elements, 1980 , vol. 9, p. 155 - 164
参考文献
Bayer and Co.
Patent: DE276331 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 12, p. 173
参考文献
Bayer and Co.
Patent: DE276331 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 12, p. 173
