(5-羟基-1-苯并呋喃-3-基)(苯基)甲酮合成路线 （共 7 条）
反应条件
in acetic acid T=20°C; 5 h; Inert atmosphere;
参考文献
Antczak, Christophe; Shum, David; Bassit, Bhramdeo; Frattini, Mark G.; Li, Yueming; Stanchina, Elisa De; Scheinberg, David A.; Djaballah, Hakim
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 15 p. 4528 - 4532
反应条件
1: N,N-dimethyl-formamide / 20 h / 150 °C / Inert atmosphere 2: acetic acid / 5 h / 20 °C / Inert atmosphere View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 15 p. 4528 - 4532
反应条件
sodium hydroxide; sodium methylate
1.) Ch3OH, reflux, 2.) reflux; Yield given. Multistep reaction;
参考文献
Grinev, A. N.; Zotova, S. A.; Mukhanova, T. I.; Lyubchanskaya, V. M.; Shvarts, G. Ya.; et al.
Pharmaceutical Chemistry Journal, 1982 , vol. 16, # 3 p. 191 - 194
Khimiko-Farmatsevticheskii Zhurnal, 1982 , vol. 16, # 3 p. 291 - 294
反应条件
bromine in acetic acid
5 h; Ambient temperature;
参考文献
Grinev, A. N.; Mukhanova, T. I.; Zinov'eva, R. A.; Alekseeva, L. M.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , p. 1044 - 1046
Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 10 p. 1314 - 1317
反应条件
bromine in chloroform
1.)reflux, 3 h 2.)r.t., 3-4 h;
参考文献
Grinev, A. N.; Mukhanova, T. I.; Zinov'eva, R. A.; Alekseeva, L. M.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , p. 1044 - 1046
Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 10 p. 1314 - 1317
反应条件
sulfuryl dichloride in chloroform
1.)-5 to -10 deg C, 2 h 2.)r.t., 15-18 h;
参考文献
Grinev, A. N.; Mukhanova, T. I.; Zinov'eva, R. A.; Alekseeva, L. M.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , p. 1044 - 1046
Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 10 p. 1314 - 1317
反应条件
nitric acid in acetic acid
5 h; Ambient temperature;
参考文献
Grinev, A. N.; Mukhanova, T. I.; Zinov'eva, R. A.; Alekseeva, L. M.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , p. 1044 - 1046
Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 10 p. 1314 - 1317
