Fmoc-L-beta-高缬氨酸合成路线 （共 11 条）
反应条件
silver benzoate in 1,4-dioxane; water T=70°C; Wolff rearrangement; 5 h;
参考文献
Synthetic Communications, , vol. 33, # 18 p. 3089 - 3096
反应条件
hydrogenchloride in 1,4-dioxane 8 h; Heating;
参考文献
Tetrahedron, , vol. 51, # 45 p. 12337 - 12350
反应条件
1: 93 percent / 1H-benzotriazol-1-yl-N-oxytrispyrrolidinophosphonium PF6(1-); N-ethyldiisopropylamine / tetrahydrofuran; dimethylformamide; diethyl ether / 0.25 h / 0 °C 2: 78 percent / silver benzoate / dioxane; H2O / 70 °C View Scheme
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 42, # 7 p. 1691 - 1695
反应条件
1: tetrahydrofuran; diethyl ether / 3 h / Ambient temperature 2: silver benzoate, H2O / dioxane / Ambient temperature View Scheme
参考文献
Synthesis, , # 6 p. 837 - 841
反应条件
1: 94 percent / triethylamine / tetrahydrofuran / 2 h 2: 78 percent / polystyryl diphenylphosphine, imidazole, iodine / CH2Cl2 / 1 h / Heating 3: 82 percent / CH2Cl2 / 4 h / Heating 4: TFA / CH2Cl2 / 1 h 5: 10 percent aq. Na2CO3 / tetrahydrofuran / 1 h / Ambient temperature 6: 91 percent / conc. aq. HCl / dioxane / 8 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 51, # 45 p. 12337 - 12350
反应条件
1: 10 percent aq. Na2CO3 / tetrahydrofuran / 1 h / Ambient temperature 2: 91 percent / conc. aq. HCl / dioxane / 8 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 51, # 45 p. 12337 - 12350
反应条件
1: 78 percent / polystyryl diphenylphosphine, imidazole, iodine / CH2Cl2 / 1 h / Heating 2: 82 percent / CH2Cl2 / 4 h / Heating 3: TFA / CH2Cl2 / 1 h 4: 10 percent aq. Na2CO3 / tetrahydrofuran / 1 h / Ambient temperature 5: 91 percent / conc. aq. HCl / dioxane / 8 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 51, # 45 p. 12337 - 12350
反应条件
1: 82 percent / CH2Cl2 / 4 h / Heating 2: TFA / CH2Cl2 / 1 h 3: 10 percent aq. Na2CO3 / tetrahydrofuran / 1 h / Ambient temperature 4: 91 percent / conc. aq. HCl / dioxane / 8 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 51, # 45 p. 12337 - 12350
反应条件
1: 10 percent aq. Na2CO3 / tetrahydrofuran / 1 h / Ambient temperature 2: 91 percent / conc. aq. HCl / dioxane / 8 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 51, # 45 p. 12337 - 12350
反应条件
1: TFA / CH2Cl2 / 1 h 2: 10 percent aq. Na2CO3 / tetrahydrofuran / 1 h / Ambient temperature 3: 91 percent / conc. aq. HCl / dioxane / 8 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 51, # 45 p. 12337 - 12350
