2'-C-甲基-6-S-甲基-6-硫代-肌苷合成路线 （共 8 条）
参考文献
GENELABS TECHNOLOGIES, INC.
Patent: WO2003/93290 A2, 2003 ;
Location in patent: Page/Page column 109 ;
反应条件
1: TMSOTf; BSA / acetonitrile / 3 h / 60 °C 2: ethanol / 4 h / 50 °C View Scheme
参考文献
Harry-O'kuru, Rogers E.; Kryjak, Emily A.; Wolfe, Michael S.
Nucleosides and Nucleotides, 1997 , vol. 16, # 7-9 p. 1457 - 1460
反应条件
1: 47 percent / N,O-bis(trimethylsilyl)acetamide, TMSOTf / acetonitrile / Heating 2: ammonia gas / methanol View Scheme
参考文献
Harry-O'kuru; Smith; Wolfe
Journal of Organic Chemistry, 1997 , vol. 62, # 6 p. 1754 - 1759
反应条件
1: 1.) CeCl3, 2.) DMAP, Et3N 2: 47 percent / bis(trimethylsilyl)acetamide, TMSOTf / acetonitrile / Heating 3: NH3/MeOH View Scheme
参考文献
Wolfe; Harry-O'kuru
Tetrahedron Letters, 1995 , vol. 36, # 42 p. 7611 - 7614
反应条件
1: TMSOTf; BSA / acetonitrile / 3 h / 60 °C 2: ethanol / 4 h / 50 °C View Scheme
参考文献
Ding, Yili; Girardet, Jean-Luc; Hong, Zhi; Lai, Vicky C.H.; An, Haoyun; Koh, Yung-Hyo; Shaw, Stephanie Z.; Zhong, Weidong
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 3 p. 709 - 713
反应条件
1: Dess-Martin periodane, MgSO4 / CH2Cl2 2: TiCl4, dimethylaminopyridine, Et3N 3: 1.) (TMSO)(TMSN)C(Me), SnCl4; 2.) NH3 / 1.) acetonitrile, reflux, 3 h; 2.) MeOH View Scheme
参考文献
Wolfe; Harry-O'kuru
Tetrahedron Letters, 1995 , vol. 36, # 42 p. 7611 - 7614
反应条件
in ethanol T=50°C; 4 h;
参考文献
Ding, Yili; Girardet, Jean-Luc; Hong, Zhi; Lai, Vicky C.H.; An, Haoyun; Koh, Yung-Hyo; Shaw, Stephanie Z.; Zhong, Weidong
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 3 p. 709 - 713
反应条件
N,O-bis-(trimethylsilyl)-acetamide; ammonia; tin(IV) chloride 1.) acetonitrile, reflux, 3 h; 2.) MeOH; Multistep reaction;
参考文献
Wolfe; Harry-O'kuru
Tetrahedron Letters, 1995 , vol. 36, # 42 p. 7611 - 7614
