3,5-二乙氧基基苯甲酸甲酯合成路线 （共 48 条）
反应条件
1: (i) LiAlH4, (ii) PBr3 2: Zn / tetrahydrofuran View Scheme
参考文献
Bullimore,B.K. et al.
Journal of the Chemical Society [Section] C: Organic, 1967 , p. 1289 - 1293
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 20 °C / |Inert atmosphere 2: hydrogenchloride / water / |Inert atmosphere 3: 10 h / 140 °C / |Inert atmosphere 4: potassium hydroxide / tetrahydrofuran / 24 h / |Inert atmosphere 5: methyl iodide; magnesium / diethyl ether / 45 - 190 °C / |Inert atmosphere View Scheme
参考文献
Jungong, Christian S.; Novikov, Alexei V.
Synthetic Communications, 2012 , vol. 42, # 24 p. 3589 - 3597,9
Title/Abstract Full Text Show Details
Jungong, Christian S.; Novikov, Alexei V.
Synthetic Communications, 2012 , vol. 42, # 24 p. 3589 - 3597
反应条件
1: (i) LiAlH4, (ii) PBr3 2: Zn / tetrahydrofuran View Scheme
参考文献
Bullimore,B.K. et al.
Journal of the Chemical Society [Section] C: Organic, 1967 , p. 1289 - 1293
反应条件
1: 84 percent / LiAlH4 / diethyl ether / 3 h / Heating 2: 86 percent / pyridine / 3 h / 20 °C 3: 78 percent / POCl3 / 3 h / 80 °C 4: 68 percent / aq. KMnO4 / dioxane / 0.75 h / 80 °C 5: 75 percent / AlCl3 / CH2Cl2 / 6 h / 20 °C View Scheme
参考文献
Paradkar, Madhusudan V.; Kulkarni, Sanjeev A.; Joseph, Augustine R.; Ranade, Anup A.
Journal of Chemical Research, Miniprint, 2000 , # 8 p. 944 - 956
反应条件
(i) LiAlH4, (ii) PBr3; Multistep reaction;
参考文献
Bullimore,B.K. et al.
Journal of the Chemical Society [Section] C: Organic, 1967 , p. 1289 - 1293
反应条件
sodium hydride in tetrahydrofuran T=20°C;
参考文献
Kim, Ikyon; Song, Jong Hwan; Park, Chang Min; Jeong, Joon Won; Kim, Hyung Rae; Ha, Jin Ryul; No, Zaesung; Hyun, Young-Lan; Cho, Young Sik; Sook Kang, Nam; Jeon, Dong Ju
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 3 p. 922 - 926
反应条件
1: 78 percent / hydrazine hydrate / 2 h / Heating 2: 63 percent / sodium nitrite, hydrochloric acid (2M), acetic acid (glacial) / H2O / 1 h / -10 °C 3: 93 percent / toluene / 2.5 h / Heating View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
反应条件
1: 78 percent / hydrazine hydrate / 2 h / Heating 2: 63 percent / sodium nitrite, hydrochloric acid (2M), acetic acid (glacial) / H2O / 1 h / -10 °C 3: 93 percent / toluene / 2.5 h / Heating 4: 8.7 g / sodium hydroxide (20percent) / 60 °C 8: 28.8 g / fluoroboric acid, sodium nitrite / H2O 9: 7.6 g / warming, distillation View Scheme
参考文献
Durrani, Aziz A.; Tyman, John H. P.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1658 - 1666
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 20 °C / |Inert atmosphere 2: hydrogenchloride / water / |Inert atmosphere View Scheme
参考文献
Jungong, Christian S.; Novikov, Alexei V.
Synthetic Communications, 2012 , vol. 42, # 24 p. 3589 - 3597,9
Title/Abstract Full Text Show Details
Jungong, Christian S.; Novikov, Alexei V.
Synthetic Communications, 2012 , vol. 42, # 24 p. 3589 - 3597
反应条件
lithium aluminium tetrahydride in diethyl ether Reduction; 3 h; Heating;
参考文献
Paradkar, Madhusudan V.; Kulkarni, Sanjeev A.; Joseph, Augustine R.; Ranade, Anup A.
Journal of Chemical Research, Miniprint, 2000 , # 8 p. 944 - 956
