2-氨基-3-溴-5-甲基吡啶合成路线 (共 23 条)
反应条件
tetrakis(triphenylphosphine) palladium(0); 1,8-diazabicyclo[5.4.0]undec-7-ene in water; tert-butyl alcohol
T=85°C; 16 h; Inert atmosphere;
参考文献
Zhang, Dengyou; Sun, Haifeng; Zhang, Lei; Zhou, Yu; Li, Chunpu; Jiang, Hualiang; Chen, Kaixian; Liu, Hong
Chemical Communications, 2012 , vol. 48, # 23 p. 2909 - 2911
反应条件
tetrakis(triphenylphosphine) palladium(0); K4[Fe(CN)6] trihydrate; 1,8-diazabicyclo[5.4.0]undec-7-ene in water; tert-butyl alcohol
T=85°C; 18 h;
参考文献
Vallerini, Gian Paolo; Amori, Laura; Beato, Claudia; Tararina, Margarita; Wang, Xiao-Dan; Schwarcz, Robert; Costantino, Gabriele
Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9482 - 9495
反应条件
in N,N-dimethyl-formamide
20 h; Heating;
参考文献
Dunn; Norrie
Advanced Synthesis and Catalysis, 1996 , vol. 338, # 7 p. 663 - 666