反应条件
1: 1.) Mg, I2 / 1.) THF, 50 deg C, 30 min, 2.) THF, r.t., 2 h; reflux, 1.5 h 2: LiBr, ZnBr2, PBr3 / tetrahydrofuran / 5 h / -60 °C 3: LDA, DMPU / tetrahydrofuran / 1.) -78 deg C, 10 min, 2.) -78 deg C, 5 h 4: AcOH, NaOAc, H2O / diethyl ether / 1 h 5: 100 percent / Et3N / benzene / 0.5 h / 0 °C 6: Me3Al/AlCl3 / benzene; tetrahydrofuran; toluene / 2 h / Ambient temperature 7: H2O, SiO2 8: 55 percent / benzene / 0 °C / Irradiation 9: TFA / CH2Cl2 / 1 h / 0 °C View Scheme
参考文献
Garst; Tallman; Bonfiglio; et al.
Tetrahedron Letters, 1986 , vol. 27, # 38 p. 4533 - 4536
