2-甲基-2-丙基(6-碘己基)氨基甲酸酯合成路线 （共 5 条）
反应条件
1H-imidazole; iodine; triphenylphosphine in diethyl ether; acetonitrile T=0°C; 1 h;
参考文献
Dutton, Jonathan K.; Knox, John H.; Radisson, Xavier; Ritchie, Harold J.; Ramage, Robert
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 20 p. 2581 - 2588
反应条件
sodium iodide in acetonitrile T=20°C; 18 h;
参考文献
Isomura; Wirsching; Janda
Journal of Organic Chemistry, 2001 , vol. 66, # 12 p. 4115 - 4121
反应条件
1: 99 percent / methanol / 1.5 h / 20 °C 2: Et3N / CH2Cl2 / 2 h / 20 °C 3: 1.8 g / NaI / acetonitrile / 18 h / 20 °C View Scheme
参考文献
Culcasi, Marcel; Casano, Gilles; Lucchesi, Celine; Mercier, Anne; Clement, Jean-Louis; Pique, Valerie; Michelet, Laure; Krieger-Liszkay, Anja; Robin, Maxime; Pietri, Sylvia
Journal of Medicinal Chemistry, 2013 , vol. 56, # 6 p. 2487 - 2499
反应条件
1: 99 percent / methanol / 1.5 h / 20 °C 2: Et3N / CH2Cl2 / 2 h / 20 °C 3: 1.8 g / NaI / acetonitrile / 18 h / 20 °C View Scheme
参考文献
Culcasi, Marcel; Casano, Gilles; Lucchesi, Celine; Mercier, Anne; Clement, Jean-Louis; Pique, Valerie; Michelet, Laure; Krieger-Liszkay, Anja; Robin, Maxime; Pietri, Sylvia
Journal of Medicinal Chemistry, 2013 , vol. 56, # 6 p. 2487 - 2499
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 - 20 °C / Inert atmosphere 1.2: 12 h / 20 °C / Inert atmosphere 2.1: 2,6-dimethylpyridine; Ir[(dF(CF3)ppy)2(dtbbpy)]PF6; trichloromonobromomethane; water / acetonitrile / 12 h / Inert atmosphere; Irradiation View Scheme
参考文献
Tucker, Joseph W.; Narayanam, Jagan M. R.; Shah, Pinkey S.; Stephenson, Corey R. J.
Chemical Communications, 2011 , vol. 47, # 17 p. 5040 - 5042
