2-氨基异丁酸乙酯盐酸盐合成路线 （共 11 条）
反应条件
1: ethanol With thionyl chloride T=0 - 20°C; 1 h; 2: 2-amino-2-methylpropionic acid Heating / reflux;
参考文献
Roche Palo Alto LLC
Patent: US2007/42988 A1, 2007 ;
Location in patent: Page/Page column 18; 22 ;
反应条件
thionyl chloride Esterification; 1 h; Heating;
参考文献
Cianci, Julia; Baell, Jonathan B.; Harvey, Andrew J.
Tetrahedron Letters, 2007 , vol. 48, # 34 p. 5973 - 5975
参考文献
Leibfritz, Dieter; Haupt, Erhard; Dubischar, Norbert; Lachmann, Heinrich; Oekonomopulos, Raymond; Jung, Guenther
Tetrahedron, 1982 , vol. 38, # 14 p. 2165 - 2182
反应条件
T=0°C; bei nachfolgendem Aufbewahren;
参考文献
Barker; Skinner
Journal of the American Chemical Society, 1924 , vol. 46, p. 412
反应条件
hydrogenchloride; sodium nitrite T=20°C;
参考文献
Barker; Skinner
Journal of the American Chemical Society, 1924 , vol. 46, p. 412
反应条件
T=0°C; bei nachfolgendem Aufbewahren;
参考文献
Barker; Skinner
Journal of the American Chemical Society, 1924 , vol. 46, p. 412
反应条件
hydrogenchloride; sodium nitrite
参考文献
Barker; Skinner
Journal of the American Chemical Society, 1924 , vol. 46, p. 412
反应条件
T=0°C; bei nachfolgendem Aufbewahren;
参考文献
Barker; Skinner
Journal of the American Chemical Society, 1924 , vol. 46, p. 412
反应条件
4 A molecular sieve in dichloromethane
参考文献
Han; Frey
Journal of the American Chemical Society, 1990 , vol. 112, # 24 p. 8982 - 8983
反应条件
triethylamine in dichloromethane
T=20°C; Acylation; 1 h;
参考文献
Collins, David J.; Hughes, Timothy C.; Johnson, Wynona M.
Australian Journal of Chemistry, 1999 , vol. 52, # 5 p. 379 - 385
