(R)-6-氧代哌啶-3-氨基甲酸叔丁酯合成路线 （共 10 条）
反应条件
hydrogen; palladium 10 on activated carbon in methanol P=2068.65 Torr; 1 h;
参考文献
GLENMARK PHARMACEUTICALS LIMITED
Patent: WO2004/22536 A1, 2004 ;
Location in patent: Page 52-53 ;
WO 2004/022536 A1
反应条件
sodium tetrahydroborate; palladium on activated charcoal in tetrahydrofuran; methanol T=20°C; 0.333333 h;
参考文献
Bellis, Evagelos; Markidis, Theodoros; Kokotos, George
Synthesis, 2002 , # 10 p. 1359 - 1364
反应条件
titanium(III) chloride; hydrogen; palladium on activated charcoal
参考文献
Panday, Sharad Kumar; Langlois, Nicole
Tetrahedron Letters, 1995 , vol. 36, # 45 p. 8205 - 8208
反应条件
1: DMAP / acetonitrile 2: NaN3 / dimethylformamide / 50 °C 3: H2 / Pd/C / methanol 4: methanol / Heating View Scheme
参考文献
Langlois, Nicole
Tetrahedron Letters, 2002 , vol. 43, # 52 p. 9531 - 9533
反应条件
1: pyridine / 0 - 20 °C 2: DMAP / acetonitrile 3: NaN3 / dimethylformamide / 50 °C 4: H2 / Pd/C / methanol 5: methanol / Heating View Scheme
参考文献
Langlois, Nicole
Tetrahedron Letters, 2002 , vol. 43, # 52 p. 9531 - 9533
反应条件
1: DMAP / acetonitrile 2: NaN3 / dimethylformamide / 50 °C 3: H2 / Pd/C / methanol 4: methanol / Heating View Scheme
参考文献
Langlois, Nicole
Tetrahedron Letters, 2002 , vol. 43, # 52 p. 9531 - 9533
反应条件
1: H2 / Pd/C / methanol 2: methanol / Heating View Scheme
参考文献
Langlois, Nicole
Tetrahedron Letters, 2002 , vol. 43, # 52 p. 9531 - 9533
反应条件
1: Et3N / CH2Cl2 / 1 h / 0 - 20 °C 2: NaN3 / dimethylformamide / 6 h / 60 °C 3: 31 percent / NaBH4 / 10 percent Pd/C / tetrahydrofuran; methanol / 0.33 h / 20 °C View Scheme
参考文献
Bellis, Evagelos; Markidis, Theodoros; Kokotos, George
Synthesis, 2002 , # 10 p. 1359 - 1364
反应条件
1: NaN3 / dimethylformamide / 6 h / 60 °C 2: 31 percent / NaBH4 / 10 percent Pd/C / tetrahydrofuran; methanol / 0.33 h / 20 °C View Scheme
参考文献
Bellis, Evagelos; Markidis, Theodoros; Kokotos, George
Synthesis, 2002 , # 10 p. 1359 - 1364
反应条件
hydrogenchloride in ethyl acetate T=20°C; 3 h;
参考文献
GLENMARK PHARMACEUTICALS LIMITED
Patent: WO2004/22536 A1, 2004 ;
Location in patent: Page 95 ;
WO 2004/022536 A1
