1,2-二溴-3,4,5-三氟苯合成路线 （共 8 条）
反应条件
n-butyllithium; n-butyl-magnesium chloride in tetrahydrofuran; hexane; toluene T=0°C; 0.75 h;
参考文献
Heiss, Christophe; Schlosser, Manfred
European Journal of Organic Chemistry, 2003 , # 3 p. 447 - 451
反应条件
n-butyllithium; diisopropylamine in tetrahydrofuran; hexane T=-75°C; 2 h;
参考文献
Heiss, Christophe; Schlosser, Manfred
European Journal of Organic Chemistry, 2003 , # 3 p. 447 - 451
反应条件
1: 91 percent / sec-butyllithium / tetrahydrofuran; cyclohexane / 1.5 h / -75 °C 2: 95 percent / bromine / CCl4 / Heating 3: diisopropylamine; butyllithium / hexane; tetrahydrofuran / 2 h / -75 °C View Scheme
参考文献
Heiss, Christophe; Schlosser, Manfred
European Journal of Organic Chemistry, 2003 , # 3 p. 447 - 451
反应条件
1: 92 percent / diisopropylamine; butyllithium / hexane; tetrahydrofuran / 2 h / -75 °C 2: 93 percent / bromine / CCl4 / 36 h / Heating 3: diisopropylamine; butyllithium / hexane; tetrahydrofuran / 2 h / -75 °C View Scheme
参考文献
Heiss, Christophe; Schlosser, Manfred
European Journal of Organic Chemistry, 2003 , # 3 p. 447 - 451
反应条件
1: 93 percent / bromine / CCl4 / 36 h / Heating 2: diisopropylamine; butyllithium / hexane; tetrahydrofuran / 2 h / -75 °C View Scheme
参考文献
Heiss, Christophe; Schlosser, Manfred
European Journal of Organic Chemistry, 2003 , # 3 p. 447 - 451
反应条件
1: 95 percent / bromine / CCl4 / Heating 2: diisopropylamine; butyllithium / hexane; tetrahydrofuran / 2 h / -75 °C View Scheme
参考文献
Heiss, Christophe; Schlosser, Manfred
European Journal of Organic Chemistry, 2003 , # 3 p. 447 - 451
反应条件
n-butyllithium in diethyl ether; hexane T=-100°C; 0.25 h;
参考文献
Heiss, Christophe; Schlosser, Manfred
European Journal of Organic Chemistry, 2003 , # 3 p. 447 - 451
反应条件
1: 89 percent / butyllithium / diethyl ether; hexane / 0.25 h / -100 °C 2: 93 percent / butyllithium / diethyl ether; hexane / 0.25 h / -75 °C View Scheme
参考文献
European Journal of Organic Chemistry, , # 3 p. 447 - 451
