(S)-(+)-2-甲基丁酸合成路线 （共 111 条）
反应条件
1: 92 percent / 85percent H2SO4 / 2 h / 110 - 120 °C 2: 1.) O3, 2.) 35percent aq. H2O2, 5percent aq. NaOH / 1.) CH2Cl2, RT, 24 h, 2.) EtOH, reflux, 24 h View Scheme
参考文献
Synthetic Communications, , vol. 22, # 18 p. 2645 - 2651
反应条件
sodium hydroxide; dihydrogen peroxide; ozone 1.) CH2Cl2, RT, 24 h, 2.) EtOH, reflux, 24 h; Yield given. Multistep reaction. Title compound not separated from byproducts;
参考文献
Synthetic Communications, , vol. 22, # 18 p. 2645 - 2651
反应条件
hydrogenchloride; lithium diisopropyl amide 1.) THF, 0 deg C, 2 h, 2.) dioxane, 90-95 deg C, 42 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 38, # 9 p. 795 - 802
反应条件
mittels des Brucinsalzes;
参考文献
Chem. Zentralbl., , vol. 68, # I p. 419
Recueil des Travaux Chimiques des Pays-Bas, , vol. 13, p. 195
反应条件
durch Einw. von Faeulnisbakterien;
参考文献
Biochemische Zeitschrift, , vol. 37, p. 494
参考文献
Biochemische Zeitschrift, , vol. 64, p. 374
参考文献
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 226, p. 1144
Ann. Inst. Pasteur, , vol. 75, p. 299
参考文献
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 226, p. 1144
Ann. Inst. Pasteur, , vol. 75, p. 299
反应条件
(+)-3,7-dimethyl-nonane-4,6-dione;
参考文献
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 227, p. 56,59, 69
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 235, p. 181
反应条件
in diethyl ether T=20°C; Esterification; 1 h;
参考文献
Tashiro, Takuya; Mori, Kenji
European Journal of Organic Chemistry, 1999 , # 9 p. 2167 - 2173
