(E)-4'-溴-beta-氯丙烯酰苯合成路线 （共 5 条）
反应条件
sodium in diethyl ether
参考文献
Belyaev,V.F.; Shamanovskaya,R.I.
Journal of Organic Chemistry USSR (English Translation), 1965 , vol. 1, p. 1405 - 1407
Zhurnal Organicheskoi Khimii, 1965 , vol. 1, p. 1388 - 1390
反应条件
1: Et3N / hexane / 2 h / under 50 deg C
2: 57percent aq. HClO4 / ethanol / 1.)r.t., 2 h 2.)0 deg C, 8 h
3: 71 percent / NH4OAc / acetic acid / 2 h / Heating
4: 82 percent / 220 - 240 °C
View Scheme
参考文献
Grebyonkin, M. F.; Petrov, V. F.; Belyaev, V. V.; Pavluchenko, A. I.; Smirnova, N. I.; et al.
Molecular Crystals and Liquid Crystals (1969-1991), 1985 , vol. 129, p. 245 - 258
反应条件
1: Et3N / hexane / 2 h / under 50 deg C
2: 57percent aq. HClO4 / ethanol / 1.)r.t., 2 h 2.)0 deg C, 8 h
3: 80 percent / NH4OAc / acetic acid / 2 h / Heating
View Scheme
参考文献
Pavlyuchenko, A. I.; Smirnova, N. I.; Kovshev, E. I.; Titov, V. V.
Journal of Organic Chemistry USSR (English Translation), 1986 , p. 957 - 960
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 5 p. 1065 - 1069
反应条件
perchloric acid; triethylamine
1.) hexane, 2.) EtOH, RT;; Yield given. Multistep reaction;
参考文献
Grebyonkin, M. F.; Petrov, V. F.; Belyaev, V. V.; Pavluchenko, A. I.; Smirnova, N. I.; et al.
Molecular Crystals and Liquid Crystals (1969-1991), 1985 , vol. 129, p. 245 - 258
反应条件
T=4°C; 72 h; optical yield given as percent de;
参考文献
Snelders, Dennis J. M.; Dyson, Paul J.
Organic Letters, 2011 , vol. 13, # 15 p. 4048 - 4051
