3',5'-二-O-乙酰基-2'-脱氧腺苷合成路线 （共 16 条）
反应条件
pyridine; 4-(N,N-dimethlyamino)pyridine 4 h; Ambient temperature;
参考文献
Van der Wenden; Von Frijtag Drabbe Kunzel; Mathot; Danhof; Ijzerman; Soudijn
Journal of Medicinal Chemistry, 1995 , vol. 38, # 20 p. 4000 - 4006
反应条件
in methanol T=105°C; 1.5 h;
参考文献
Nowak, Ireneusz; Conda-Sheridan, Martin; Robins, Morris J.
Journal of Organic Chemistry, 2005 , vol. 70, # 18 p. 7455 - 7458
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile 18 h; Ambient temperature;
参考文献
Himmelsbach, Frank; Schulz, Bernd S.; Trichtinger, Thomas; Charubala, Ramamurthy; Pfleiderer, Wolfgang
Tetrahedron, 1984 , vol. 40, # 1 p. 59 - 72
反应条件
1: pyridine / Heating 2: 86 percent / methanol / 1.5 h / 105 °C View Scheme
参考文献
De Boer; Petra; Wanner; Boesaart; Koomen
Nucleosides and Nucleotides, 1995 , vol. 14, # 3-5 p. 349 - 352
参考文献
Ferreira, Fernando; Vasseur, Jean-Jacques; Morvan, Francois
Tetrahedron Letters, 2004 , vol. 45, # 33 p. 6287 - 6290
反应条件
in pyridine Ambient temperature;
参考文献
Koole, Leo H.; Buck, Henk M.; Kanters, Jan A.; Schouten, Arie
Canadian Journal of Chemistry, 1987 , vol. 65, p. 326 - 331
反应条件
chloro-trimethyl-silane; BnEt3NNO2 in dichloromethane T=0°C;
参考文献
Francom, Paula; Robins, Morris J.
Journal of Organic Chemistry, 2003 , vol. 68, # 2 p. 666 - 669
反应条件
tert.-butylnitrite; trimethylsilyl bromide; 1,1-dibromomethane T=0 - 5°C;
参考文献
Francom, Paula; Robins, Morris J.
Journal of Organic Chemistry, 2003 , vol. 68, # 2 p. 666 - 669
反应条件
1: t-BuONO; Et4NCl / CCl4; CH2Cl2 / 4.5 h / 0 - 50 °C 2: 76 percent / NH3 / methanol / 9 h / 0 °C View Scheme
参考文献
Ikejiri, Masahiro; Saijo, Masayuki; Morikawa, Shigeru; Fukushi, Shuetsu; Mizutani, Tetsuya; Kurane, Ichiro; Maruyama, Tokumi
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 9 p. 2470 - 2473
反应条件
n-butyllithium; 2,2,2-trifluoroethanol in hexane T=20°C; 3.5 h;
参考文献
Journal of Organic Chemistry, , vol. 71, # 8 p. 3077 - 3081
