4-Beta-羟基胆固醇合成路线 （共 24 条）
反应条件
selenium(IV) oxide; acetic acid in toluene T=90°C; 1.5 h;
参考文献
Carvalho, Joao F.S.; Silva, M. Manuel Cruz; Sa e Melo, M. Luisa
Tetrahedron, 2009 , vol. 65, # 14 p. 2773 - 2781
Title/Abstract Full Text View citing articles Show Details
Carvalho, Joao F. S.; Cruz Silva, M. Manuel; Moreira, Joao N.; Simoes, Sergio; Sa E Melo, M. Luisa
Journal of Medicinal Chemistry, 2009 , vol. 52, # 13 p. 4007 - 4019
反应条件
selenium(IV) oxide in tetrahydrofuran 24 h; Reflux; regioselective reaction;
参考文献
Tetrahedron, , vol. 68, # 32 p. 6485 - 6491
反应条件
selenium(IV) oxide in chloroform 48 h; Inert atmosphereReflux;
参考文献
European Journal of Medicinal Chemistry, , vol. 70, p. 558 - 567
反应条件
selenium(IV) oxide in 1,4-dioxane; water T=100°C; 24 h; regioselective reaction;
参考文献
Tetrahedron, , vol. 68, # 32 p. 6485 - 6491
反应条件
potassium hydroxide in methanol T=20°C; 1 h;
参考文献
Poza, Javier; Rega, Miriam; Paz, Vanessa; Alonso, Beatriz; Rodriguez, Jaime; Salvador, Nelida; Fernandez, Antonio; Jimenez, Carlos
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 14 p. 4722 - 4740
反应条件
sodium borodeuteride; triphenylphosphine; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=75°C; Yield given. Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 32, # 43 p. 6081 - 6084
反应条件
sodium carbonate in methanol T=20°C; Deacetylation;
参考文献
Chemistry and Physics of Lipids, , vol. 99, # 1 p. 33 - 71
反应条件
in 1,2,3,4-tetrahydro-naphthalene T=190°C; 1.25 h;
参考文献
Boivin, Jean; Kaim, Laurent El; Kervagoret, Jocelyne; Zard, Samir Z.
Journal of the Chemical Society, Chemical Communications, 1989 , # 15 p. 1006 - 1008
反应条件
potassium hydroxide in methanol T=20°C;
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 55, # 2 p. 61 - 65
反应条件
1: SeO2; KH2PO4 / toluene / Heating 2: Na2CO3 / methanol / 20 °C View Scheme
参考文献
Chemistry and Physics of Lipids, , vol. 99, # 1 p. 33 - 71
