1: oxalyl chloride, DMF / CH2Cl2 / 1 h / 0 deg C, 30 min, r.t. 30 min 2: 84 percent / AlCl3 / CH2Cl2 / 0.5 h / Ambient temperature View Scheme

<b>Multi-step reaction with 5 steps<br /> </b>1: 88 percent / KOH / 2 h / 120 &deg;C<br />2: 83 percent / NaH / 1,2-dimethoxy-ethane / 1 h / 60 &deg;C<br />3: 100 percent / H₂ / 10percent Pd/C / ethyl acetate / 2 h / 2550.2 Torr / Ambient temperature<br />4: 89 percent / pyridine / CH₂Cl₂ / 1 h / Ambient temperature<br />5: 86 percent / NaOH / ethanol; H₂O / 2 h / Heating<br /> <br /> &nbsp;