2-(3-溴苯基)-5-甲基-1,3,4-噻二唑合成路线 (共 1 条)
反应条件
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 3 h / 50 °C 2: Lawesson's reagent / 1,4-dioxane / 1 h / 100 °C View Scheme
参考文献
MERCK SHARP and DOHME CORP.; YOUNG, Jonathan; CZAKO, Barbara; ALTMAN, Michael; GUERIN, David; MARTINEZ, Michelle; RIVKIN, Alexey; WILSON, Kevin; LIPFORD, Kathryn; WHITE, Catherine; SURDI, Laura; CHICHETTI, Stephanie; DANIELS, Matthew, H.; AHEARN, Sean, P.; FALCONE, Danielle; OSIMBONI, Ekundayo
Patent: WO2011/84402 A1, 2011 ;