2-氯-4-甲氧基吡啶-3-胺合成路线 （共 2 条）
反应条件
1: With hydrogenchloride; dihydrogen peroxide in water T=0 - 20°C; 1 h; 2: With sodium hydrogencarbonate in water
参考文献
Brinkman, John A.; Cheung, Adrian Wai-Hing; Firooznia, Fariborz; Guertin, Kevin Richard; Marcopulos, Nicholas; Qi, Lida; Racha, Jagdish Kumar; Sarabu, Ramakanth; Tan, Jenny; Tilley, Jefferson Wright
Patent: US2007/270433 A1, 2007 ;
Location in patent: Page/Page column 47 ;
US 20070270433 A1
反应条件
1: pyridine / dioxane; cyclohexane / Heating 2: xylene / Heating 3: NaH / various solvent(s) / Heating View Scheme
参考文献
Hargrave, Karl D.; Proudfoot, John R.; Grozinger, Karl G.; Cullen, Ernest; Kapadia, Suresh R.; et al.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 7 p. 2231 - 2241
