5-己基-2,2-二噻吩合成路线 （共 13 条）
反应条件
1: 2-(thien-2-yl)thiophene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; Inert atmosphere; 2: 1-bromo-hexane in tetrahydrofuran; hexane T=-78 - 20°C; 12 h; Inert atmosphere;
参考文献
Tetrahedron, , vol. 69, # 38 p. 8191 - 8198
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran 24 h; RefluxInert atmosphere;
参考文献
WO2010/12710 A1, ;
Page/Page column 18 ;
反应条件
1: thien-2-yl bromide With magnesium in diethyl ether 4 h; Inert atmosphereReflux; 2: 2-bromo-5-n-hexylthiophene With [1,3-bis(diphenylphosphino) propane] dichloronickel(II) in diethyl ether 48 h; Inert atmosphereReflux;
参考文献
Chemistry - An Asian Journal, , vol. 7, # 1 p. 225 - 232
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium hydrogencarbonate in tetrahydrofuran; water Inert atmosphereReflux;
参考文献
Organic Letters, , vol. 11, # 12 p. 2563 - 2566
反应条件
potassium hydroxide; hydrazine hydrate in various solvent(s) T=190°C; 4 h;
参考文献
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, , vol. 51, # 2 p. 286 - 294
反应条件
1: NBS / tetrahydrofuran / 20 °C 2: Mg / Ni(dppp)Cl2 / diethyl ether / Heating View Scheme
参考文献
Molecular Crystals and Liquid Crystals, , vol. 410, p. 1/[529]-12/[540]
反应条件
[1,3-bis(diphenylphosphino) propane] dichloronickel(II) in diethyl ether Tamao coupling reaction; Heating;
参考文献
Molecular Crystals and Liquid Crystals, , vol. 436, p. 225/[1179]-235/[1189]
反应条件
1: benzene / 0.25 h / 0 °C 2: 3.40 g / LiAlH4; AlCl3 / toluene; diethyl ether / 1 h / 20 °C View Scheme
参考文献
Organic Letters, , vol. 6, # 2 p. 273 - 276
反应条件
1: benzene / 0.25 h / 0 °C 2: 3.40 g / LiAlH4; AlCl3 / toluene; diethyl ether / 1 h / 20 °C View Scheme
参考文献
Organic Letters, , vol. 6, # 2 p. 273 - 276
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / 1.5 h / -60 - 0 °C / Inert atmosphere 1.2: -60 - 20 °C / Inert atmosphere 2.1: N-bromosuccinmide / N,N-dimethyl-formamide / 20 °C / Darkness 3.1: magnesium / diethyl ether / 4 h / Inert atmosphere; Reflux 3.2: 48 h / Inert atmosphere; Reflux View Scheme
参考文献
Chemistry - An Asian Journal, , vol. 7, # 1 p. 225 - 232
