4-氯-6-(4-甲氧基苯基)-7h-吡咯并[2,3-d]嘧啶合成路线 （共 3 条）
反应条件
trichlorophosphate 2.5 h; RefluxInert atmosphere;
参考文献
Sorum, Christopher; Simic, Nebojsa; Sundby, Eirik; Hoff, Bard Helge
Magnetic Resonance in Chemistry, 2010 , vol. 48, # 3 p. 244 - 248
反应条件
1.1: formic acid / N,N-dimethyl-formamide / 20 h / 150 °C 2.1: trichlorophosphate / 3 h / 90 °C 2.2: pH 12 View Scheme
参考文献
Kaspersen, Svein Jacob; Hoff, Bard Helge; Sundby, Eirik; Charnock, Colin
Bioorganic Chemistry, 2012 , vol. 44, p. 35 - 41,7
反应条件
1.1: sodium ethanolate / ethanol / 0.33 h / 0 °C / Inert atmosphere 1.2: 1.5 h / 60 °C 2.1: formic acid / N,N-dimethyl-formamide / 20 h / 150 °C 3.1: trichlorophosphate / 3 h / 90 °C 3.2: pH 12 View Scheme
参考文献
Kaspersen, Svein Jacob; Hoff, Bard Helge; Sundby, Eirik; Charnock, Colin
Bioorganic Chemistry, 2012 , vol. 44, p. 35 - 41,7
