17356-08-0合成路线 （共 1741 条）
反应条件
in neat (no solvent) byproducts: water, ammonia; mixt. (molar ratio Sn-compd.:thiourea=2:1) heating up to 250°C in 1 h (gradual evacuation from 50 to 1.33 hPa); distn. of Bu3SnNCS after no water and ammonia came off; (Bu3Sn)2S isolation from residue;
参考文献
Gordetsov, A. S.; Latyaeva, V. N.; Bogdarin, Yu. A.; Boyarinov, G. A.; Dergunov, Yu. I.
Journal of General Chemistry USSR (English Translation), 1982 , vol. 52, p. 770 - 774
Zhurnal Obshchei Khimii, 1982 , vol. 52, p. 885 - 890
参考文献
Arya,V.P. et al.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1977 , vol. 15, p. 473 - 477
反应条件
4-(pyrid-2-yl)pyridine; potassium tert-butylate in ammonia T=-40°C; electrolysis;
参考文献
Combellas; Dellerue; Mathey; Thiebault
Tetrahedron Letters, 1997 , vol. 38, # 4 p. 539 - 542
反应条件
iodine Hantzsch thiazole synthesis;
参考文献
Karpov; Nazarenko; Pekarevskii; Potekhin
Russian Journal of Applied Chemistry, 2001 , vol. 74, # 6 p. 998 - 1001
参考文献
Muthyala, Manoj Kumar; Kumar, Anil
Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 4 p. 959 - 964
反应条件
in methanol Heating / reflux;
参考文献
US2006/160857 A1, ;
Page/Page column 56 ;
US 20060160857 A1
反应条件
1: cyclopropane carboxylic acid cyanide With bromine in methanol T=0 - 25°C; 0.75 h; 2: thiourea in ethanol 1 h; Heating / reflux; 3: With sodium hydrogencarbonate in water T=17 - 25°C;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2006/40520 A1, 2006 ;
Location in patent: Page/Page column 163-164 ;
WO 2006/040520 A1
反应条件
iodine T=100°C; 8 h;
参考文献
Koppireddi, Satish; Komsani, Jayaram Reddy; Avula, Sreenivas; Pombala, Sujitha; Vasamsetti, Satishbabu; Kotamraju, Srigiridhar; Yadla, Rambabu
European Journal of Medicinal Chemistry, 2013 , vol. 66, p. 305 - 313
反应条件
in ethanol T=80°C; Hantzsch thiazole synthesis; 0.166667 h; Microwave irradiation;
参考文献
Gaikwad, Sudhakar A.; Patil, Amol A.; Deshmukh, Madhukar B.
Phosphorus, Sulfur and Silicon and the Related Elements, 2010 , vol. 185, # 1 p. 103 - 109
反应条件
sodium hydroxide 1.) EtOH, reflux; Multistep reaction;
参考文献
Somogyi, Arpad; Kane, Thomas E.; Ding, Jian-Mei; Wysocki, Vicki H.
Journal of the American Chemical Society, 1993 , vol. 115, # 12 p. 5275 - 5283
