17356-08-0合成路线 （共 1741 条）
反应条件
hydrogen bromide in water
T=60°C; 0.5 h; Reflux;
参考文献
Dunn, Derek; Hostetler, Greg; Iqbal, Mohamed; Marcy, Val R.; Lin, Yin Guo; Jones, Bruce; Aimone, Lisa D.; Gruner, John; Ator, Mark A.; Bacon, Edward R.; Chatterjee, Sankar
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 11 p. 3751 - 3753
参考文献
Gronski,P. et al.
Chemische Berichte, 1977 , vol. 110, p. 3689 - 3702
反应条件
in ethanol
6 h; Heating / reflux;
参考文献
Sanofi-Synthelabo
Patent: US2005/182104 A1, 2005 ;
Location in patent: Page/Page column 7 ;
反应条件
in ethanol
T=20°C; 1 h;
参考文献
Weinstein, David S.; Gilmore, John L.; Sheppeck, James; Yang, Bingwei Vera; Kim, Soong-Hoon; Vaccaro, Wayne
Patent: US2005/187242 A1, 2005 ;
Location in patent: Page/Page column 33 ;
反应条件
in ethanol
T=20°C; 1 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2005/72732 A1, 2005 ;
Location in patent: Page/Page column 58 ;
WO 2005/072732 A1
反应条件
in ethanol
T=20°C; 2 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: WO2008/57862 A2, 2008 ;
Location in patent: Page/Page column 79 ;
反应条件
in butan-1-ol
5 h; Heating;
参考文献
Sayed; Hamed; Meligi; Boraie; Shafik
Molecules, 2003 , vol. 8, # 3 p. 322 - 332
参考文献
Buehler,C.A. et al.
Journal of Medicinal Chemistry, 1963 , vol. 6, p. 230 - 233
参考文献
Moore; Crossley
Journal of the American Chemical Society, 1940 , vol. 62, p. 3274
反应条件
in toluene
2 h; Heating;
参考文献
Boyer, Cecile; Finazzi, Giovanni; Laurent, Philippe; Haas, Alois; Blancou, Hubert
Journal of Fluorine Chemistry, 2006 , vol. 127, # 11 p. 1522 - 1527
