17356-08-0合成路线 （共 1741 条）
反应条件
1.) EtOH, steam-bath, 2.) room temperature, 16 h;
参考文献
Hardy, Kenneth D.; Harrington, Frank P.; Stachulski, Andrew V.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 6 p. 1227 - 1236
反应条件
sodium ethanolate in ethanol
17.5 h; Heating;
参考文献
Wong; McKeown
Journal of Pharmaceutical Sciences, 1988 , vol. 77, # 11 p. 926 - 932
参考文献
Merck
Patent: DE235801 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 10, p. 1153
参考文献
Merck
Patent: DE163200 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 8, p. 1084
参考文献
Merck
Patent: DE182764 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 8, p. 1061
反应条件
sodium ethanolate
Erwaermen des Reaktionsprodukts mit wss. H2SO4;
参考文献
I.G. Farbenind.
Patent: DE692928 , 1935 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 24, p. 354
反应条件
hydrogenchloride in acetic acid
T=90 - 95°C; 1 h;
参考文献
MERCK and CO., INC.
Patent: WO2003/91239 A1, 2003 ;
Location in patent: Page/Page column 51 ;
WO 03/091239 A1
反应条件
in ethanol
18 h; Heating / reflux;
参考文献
BAYER PHARMACEUTICALS CORPORATION
Patent: WO2006/121904 A1, 2006 ;
Location in patent: Page/Page column 57 ;
反应条件
methanol; sodium
1.) Et2O, 0 deg C, 1 h, 2.) MeOH, reflux, 4 h; Multistep reaction;
参考文献
Barton, Anne; Breukelman, Stephen P.; Kaye, Perry T.; Meakins, G. Denis; Morgan, David J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 159 - 164
反应条件
1: in ethanol
12 h; Heating;
2: With potassium hydroxide in ethanol
4 h; Heating;
参考文献
Lee, Jungkyu K.; Kim, Yang-Gyun; Chi, Young Shik; Yun, Wan Soo; Choi, Insung S.
Journal of Physical Chemistry B, 2004 , vol. 108, # 23 p. 7665 - 7673
