17356-08-0合成路线 （共 1741 条）
反应条件
sodium hydroxide in ethanol
2 h; Heating;
参考文献
Sayed
Egyptian Journal of Chemistry, 2005 , vol. 48, # 2 p. 223 - 234
反应条件
in ethanol
18 h; Heating / reflux;
参考文献
SIRTRIS PHARMACEUTICALS, INC.
Patent: WO2009/14674 A1, 2009 ;
Location in patent: Page/Page column 86-87 ;
WO 2009/014674 A1
反应条件
ethanol; sodium ethanolate
参考文献
Croxall; Fegley
Journal of the American Chemical Society, 1950 , vol. 72, p. 2888
反应条件
ethanol; sodium ethanolate
参考文献
Croxall; Fegley
Journal of the American Chemical Society, 1950 , vol. 72, p. 2888
反应条件
H3[PW12O40]
T=90°C; Biginelli Pyrimidone Synthesis; 4 h; Ionic liquidSchlenk technique;
参考文献
Alvim, Haline G. O.; De Lima, Tatiani B.; De Oliveira, Heibbe C. B.; Gozzo, Fabio C.; De MacEdo, Julio L.; Abdelnur, Patricia V.; Silva, Wender A.; Neto, Brenno A. D.
ACS Catalysis, 2013 , vol. 3, # 7 p. 1420 - 1430
反应条件
DPAT in ethanol
Pseudo Biginelli like reaction; 5 h; Reflux;
参考文献
Li, Jianjun; Sun, Jian; Su, Weike
Letters in Organic Chemistry, 2010 , vol. 7, # 4 p. 314 - 318
反应条件
1: in ethanol
T=70°C; 1 h;
2: With sodium carbonate in water
pH=~ 7.5;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2005/103050 A2, 2005 ;
Location in patent: Page/Page column 179-180 ;
WO 2005/103050 A2
反应条件
1: in ethanol
T=70°C; 1 h;
2: With ammonia in water
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2005/103050 A2, 2005 ;
Location in patent: Page/Page column 180-181 ;
WO 2005/103050 A2
反应条件
in ethanol
T=80°C; 1.5 h;
参考文献
UNIVERSITY OF ROCHESTER; BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA; GELBARD, Harris A.; DEWHURST, Stephen; GENDELMAN, Howard E.
Patent: WO2014/85795 A1, 2014 ;
Location in patent: Paragraph 0419 ;
参考文献
Robins
Journal of the American Chemical Society, 1958 , vol. 80, p. 6671,6675
