(R)-(+)-4-(二苯基甲基)-2-恶唑烷酮合成路线 (共 6 条)
反应条件
diphenyl phosphoryl azide; triethylamine in toluene T=80°C; 8 h;
参考文献
Takacs; Jaber; Vellekoop
Journal of Organic Chemistry, 1998 , vol. 63, # 8 p. 2742 - 2748
反应条件
sodium in ammonia 0.25 h;
参考文献
Sibi, Mukund P.; Deshpande, Prasad K.; Loggia, Anthony J. La; Christensen, James W.
Tetrahedron Letters, 1995 , vol. 36, # 49 p. 8961 - 8964
反应条件
lithium hexamethyldisilazane 1.) THF, -78 deg C, 10 min, 2.) THF, -78 deg, 10 min; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 62, # 17 p. 5864 - 5872
反应条件
lithium hexamethyldisilazane 1.) THF, -78 deg C, 10 min, 2.) THF, -78 deg, 10 min; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 62, # 17 p. 5864 - 5872
反应条件
1: 95 percent / TEA / tetrahydrofuran 2: 88 percent / Cs2CO3 / methanol 3: 80 percent / Jones reagent View Scheme
参考文献
Sibi, Mukund P.; Deshpande, Prasad K.; Loggia, Anthony J. La; Christensen, James W.
Tetrahedron Letters, 1995 , vol. 36, # 49 p. 8961 - 8964
反应条件
1: 95 percent / TEA / tetrahydrofuran 2: 88 percent / Cs2CO3 / methanol View Scheme
参考文献
Sibi, Mukund P.; Deshpande, Prasad K.; Loggia, Anthony J. La; Christensen, James W.
Tetrahedron Letters, 1995 , vol. 36, # 49 p. 8961 - 8964