N-(4-甲氧基苄基)-4-氯-2-三氟乙酰苯胺合成路线 （共 11 条）
反应条件
1: 98 percent / acetic acid / H2O / 3 h / 60 °C
2: 86 percent / m-xylene / 4 h / Heating
3: 94 percent / n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -50 °C
4: 6.8 g / triethylamine; 4-(dimethylamino)pyridine / CH2Cl2 / 1 h / 22 °C
5: aqueous KOH / propan-2-ol / 2.5 h / Heating
6: 51 mg / ceric ammonium nitrate / H2O; acetonitrile / 3.5 h / 23 °C
View Scheme
参考文献
Magnus, Nicholas A.; Confalone, Pat N.; Storace, Louis; Patel, Mona; Wood, Christopher C.; Davis, Wayne P.; Parsons Jr., Rodney L.
Journal of Organic Chemistry, 2003 , vol. 68, # 3 p. 754 - 761
